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Table 3 Associations between SNPs and asthma at school age adjusted for cord blood YKL-40 levels

From: CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development

  Univariable association Univariable association adjusted for YKL-40 levels
  OR 95 % CI P-value OR 95 % CI P-value
Exposure Outcome asthmaa
SNP*       
 rs10920579 0.25 0.06–1.15 0.305 0.23 0.05–1.08 0.254
 rs880633 1.33 0.63–2.89 0.777 1.27 0.59–2.75 0.654
 rs10399931 0.21 0.05–0.95 0.212 0.2 0.04–0.89 0.189
 rs10399805 4.50 1.59–12.94 0.031 4.76 1.66–13.62 0.026
 rs1538372 0.74 0.31–1.72 0.777 0.71 0.31–1.68 0.654
 rs7542294 2.80 1.29–7.01 0.158 2.66 1.06–6.72 0.189
 rs2486064 0.89 0.42–1.91 0.777 0.84 0.39–1.81 0.654
  1. CI Confidence interval, OR Odds ratio. SNP Single nucleotide polymorphism. aAsthma was diagnosed if one on the following was present in the previous year: (1) physician diagnosis of asthma or (2) episodic wheeze. Missing data on n = 7; data available for n = 135. * P-values for SNPs are shown after correction for multiple testing according to Benjamini-Hochberg