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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: The MK2/HuR signaling pathway regulates TNF-α-induced ICAM-1 expression by promoting the stabilization of ICAM-1 mRNA

Fig. 1

The effect of MK2 on TNF-α-induced HuR expression in HPMECs. The Western blot band density data showed that MK2 knockdown greatly reduced the levels of MK2 (a) and phospho-MK2 (b). MK2 silencing had no effect on HuR mRNA levels (c) and HuR protein levels (d). Band density and mRNA data are expressed as mean ± SEM. n =3, #P <0.05 vs. negative control siRNA-transfected cells; *P <0.05 vs. cells at TNF-α 0 h. Control siRNA, negative control siRNA; P-MK2, phospho-MK2

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