Table 3 NGS run metrics for false negative results samples
Id | Mutation | Mean read depth | Hotspot coverage | Hotspot relative coverage | Variant frequency (%) | Variant coverage | Tumor cell content (%) | DNA concentration (ng/μl) |
|---|---|---|---|---|---|---|---|---|
BM 65 | L858R | 1039 | 435 | 0.41 | 4.6 | 20 | 10 | 5.05 |
BM 76 | DEL19 | 891 | 1028 | 1.15 | 2.9 | 29 | 2 | 22.9 |
BM 145 | DEL19 | 36 | 2 | 0.05 | 100 | 2 | 14 | 4.91 |
BM 159 | L858R | 480 | 322 | 0.66 | 2.2 | 7 | 3 | 11.9 |
BM 160 | L858R | 436 | 299 | 0.68 | 4.4 | 13 | 5 | 0.22 |