Variable
| |
Univariate logistic analysis
|
Multivariate logistic analysis
|
---|
N (%)
|
OR
|
95 % Cl
|
p-value
|
OR
|
95 % Cl
|
p-value
|
---|
Age, years
|
209
| | | | | | |
<60
|
17 (8.1)
|
ref
| | |
ref
| | |
60–69
|
52 (24.9)
|
1.12
|
0.374–3.362
|
0.839
| | | |
70–79
|
98 (46.9)
|
1.83
|
0.647–5.196
|
0.254
| | | |
≥80
|
42 (20.1)
|
3.78
|
1.110–12.858
|
0.033
|
2.94
|
1.044–8.303
|
0.041
|
Male
|
172 (82.3)
|
1.41
|
0.681–2.930
|
0.354
| | | |
BMI, kg/m2
|
178
| | | | | | |
<18.5
|
27 (15.2)
|
ref
| | | | | |
18.5–25
|
114 (64.0)
|
1.43
|
0.604–3.388
|
0.415
| | | |
>25
|
37 (20.8)
|
1.13
|
0.409–3.117
|
0.814
| | | |
Brinkman Index
|
184
| | | | | | |
0
|
68 (37.0)
|
ref
| | | | | |
1–800
|
45 (24.5)
|
1.37
|
0.617–3.046
|
0.439
| | | |
>800
|
71 (33.6)
|
1.14
|
0.571–2.271
|
0.712
| | | |
F, H-J Classification scale
|
166
| | | | | | |
1–4
|
41 (24.7)
|
ref
| | |
ref
| | |
5
|
125 (75.3)
|
2.53
|
1.229–5.187
|
0.012
|
2.13
|
0.931–4.856
|
0.073
|
Specialty hospital care
|
173 (82.8)
|
0.83
|
0.382–1.799
|
0.635
| | | |
Ambulance transfer
|
101 (48.3)
|
1.22
|
0.686–2.164
| | | | |
Performing bronchoscopy
|
20 (9.6)
|
0.19
|
0.068–0.506
|
0.001
|
0.25
|
0.079–0.798
|
0.019
|
Sivelestat
|
104 (49.8)
|
0.87
|
0.489–1.538
|
0.626
| | | |
Diuretic drug
|
102 (48.8)
|
0.82
|
0.461–1.451
|
0.493
| | | |
Anticoagulant therapy
|
87 (41.6)
|
0.52
|
0.292–0.933
|
0.028
| | | |
Immunosuppressive therapy
|
75 (35.9)
|
0.66
|
0.366–1.193
|
0.17
| | | |
Intravenous high-dose cyclophosphamide
|
32 (15.3)
|
1.38
|
0.601–3.160
|
0.449
|
3.17
|
1.101–9.148
|
0.033
|
PMX
|
13 (6.2)
|
1.17
|
0.347–3.935
|
0.801
| | | |
Recombinant human soluble thrombomodulin
|
9 (4.3)
|
1.03
|
0.250–4.247
|
0.967
| | | |
Antibiotic therapy
|
206 (98.6)
|
–
|
–
| | | | |
β-Lactams
|
176 (84.2)
|
0.97
|
0.440–2.126
|
0.933
| | | |
Co-trimoxazole
|
115 (55.0)
|
0.20
|
0.103–0.388
|
<0.001
| |
0.28
|
0.132–0.607
|
Quinolones
|
103 (49.3)
|
0.77
|
0.436–1.372
|
0.38
| | | |
Macrolides
|
48 (23.0)
|
0.46
|
0.239–0.893
|
0.022
| |
0.37
|
0.155–0.867
|
Tetracycline
|
18 (8.6)
|
1.03
|
0.370–2.875
|
0.952
| | | |
Anti-MRSA antibiotics
|
17 (8.1)
|
0.94
|
0.332–2.651
|
0.904
| | | |
Clindamycin
|
5 (2.4)
|
0.33
|
0.054–2.042
|
0.235
| | | |
Aminoglycoside
|
3 (1.4)
|
0.25
|
0.022–2.826
|
0.264
| | | |
Others
|
12 (5.7)
|
0.71
|
0.216–2.307
|
0.564
| | | |
- Data are presented as n (%), unless otherwise indicated. Definition of abbreviations: BMI body mass index, F, H-J Fletcher, Hugh-Jones, PMX Direct hemoperfusion with polymyxin B-immobilized fiber, MRSA Methicillin-resistant Staphylococcus aureus