Characteristics
|
Asthma patients n = 8
|
Healthy subjects n = 10
|
---|
Age (years)
|
32.0 ± 3.4
|
26.2 ± 0.9
|
Gender (M/F), n
|
3/5
|
3/7
|
FEV1 (L)
|
3.92 ± 0.23
|
3.68 ± 0.21
|
FEV1 (% of predicted)
|
109.6 ± 3.6
|
100.7 ± 2.7
|
Wheal diameter induced by allergen (mm)
|
4.8 ± 0.6
|
0
|
PD20 (mg)
|
0.11a
|
–
|
Blood eosinophil count (x 109/L)
|
0.23 ± 0.05*
|
0.12 ± 0.01
|
Sputum eosinophil count (× 109/L)
|
0.09 ± 0.01*
|
0.03 ± 0.004
|
- F female, M male
- FEV1 – forced expiratory volume in one second
- PD20 – the provocation dose of methacholine causing a 20 % decrease in FEV1
- Data presented as Mean ± standard error of the mean
- *p < 0.01 comparing with healthy subjects peripheral eosinophils count
- aGeometric mean