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Table 1 Demographic, clinical and laboratory data of study subjects

From: Eosinophils enhance WNT-5a and TGF-β1 genes expression in airway smooth muscle cells and promote their proliferation by increased extracellular matrix proteins production in asthma

Characteristics Asthma patients n = 8 Healthy subjects n = 10
Age (years) 32.0 ± 3.4 26.2 ± 0.9
Gender (M/F), n 3/5 3/7
FEV1 (L) 3.92 ± 0.23 3.68 ± 0.21
FEV1 (% of predicted) 109.6 ± 3.6 100.7 ± 2.7
Wheal diameter induced by allergen (mm) 4.8 ± 0.6 0
PD20 (mg) 0.11a
Blood eosinophil count (x 109/L) 0.23 ± 0.05* 0.12 ± 0.01
Sputum eosinophil count (× 109/L) 0.09 ± 0.01* 0.03 ± 0.004
  1. F female, M male
  2. FEV1 – forced expiratory volume in one second
  3. PD20 – the provocation dose of methacholine causing a 20 % decrease in FEV1
  4. Data presented as Mean ± standard error of the mean
  5. *p < 0.01 comparing with healthy subjects peripheral eosinophils count
  6. aGeometric mean