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Table 1 Demographic, clinical and laboratory data of study subjects

From: Eosinophils enhance WNT-5a and TGF-β1 genes expression in airway smooth muscle cells and promote their proliferation by increased extracellular matrix proteins production in asthma

Characteristics

Asthma patients n = 8

Healthy subjects n = 10

Age (years)

32.0 ± 3.4

26.2 ± 0.9

Gender (M/F), n

3/5

3/7

FEV1 (L)

3.92 ± 0.23

3.68 ± 0.21

FEV1 (% of predicted)

109.6 ± 3.6

100.7 ± 2.7

Wheal diameter induced by allergen (mm)

4.8 ± 0.6

0

PD20 (mg)

0.11a

–

Blood eosinophil count (x 109/L)

0.23 ± 0.05*

0.12 ± 0.01

Sputum eosinophil count (× 109/L)

0.09 ± 0.01*

0.03 ± 0.004

  1. F female, M male
  2. FEV1 – forced expiratory volume in one second
  3. PD20 – the provocation dose of methacholine causing a 20 % decrease in FEV1
  4. Data presented as Mean ± standard error of the mean
  5. *p < 0.01 comparing with healthy subjects peripheral eosinophils count
  6. aGeometric mean
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BMC Pulmonary Medicine

ISSN: 1471-2466

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