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Table 1 Characteristics of cases and controls. Represented as count and percent of subgroup (N, %) or as median and interquartile range (IQR). P value determined McNemar chi-squared test, or paired samples t test using natural log transformed measures

From: Humoral immune factors and asthma among American Indian children: a case–control study

 

Cases

Controls

 

N = 108

N = 216

Characteristic

Median or N (%)

Min - Max

Median or N (%)

Min - Max

P value

95 % CI (mean)

95 % CI (mean)

Male, N (%)

57 (53 %)

43.4–63.2

109 (51 %)

57.1–43.8

0.634

Age (years)

11.81

6.1–17.9

12.12

6.1–18.3

0.001

11.4–12.2

11.7–12.6

BMI (kg/m2)

24.4

14.6–62.1

21.9

10.8–45.4

0.004

24.3–26.5

22.7–24.4

White Blood Cells (WBC) (X 1000)

7.30

3.3–16.5

6.80

2.7–14.7

0.001

7.2–7.9

6.7–7.1

PMNsa (% of WBC)

54.7

25.7–85.1

56.2

3.6–85.5

0.398

53.4–56.1

54.7–57.5

Lymphocytes (%)

30.9

9.0–65.6

30.8

12.0–54.8

0.797

30.4–32.8

30.2–35.5

Basophils (%)

1.3

0.5–6.3

1.5

0.3–17.0

0.273

1.4–1.6

1.5–1.9

Eosinophils (%)

4.1

0.3–22.3

2.7

0.1–27.2

0.002

4.8–5.6

3.3–4.2

CRP (mg/L)

1.12

0.35–17.2

1.07

0.36–74.4

0.254

2.0–2.8

1.4–3.5

IgEb (total, kU/L)

213

3.0–4473

89

2.0–2676

0.001

382.6–573.9

169.1–271.0

IgE, Alternariac

24 (22 %)

14.4–30.1

11 (5 %)

2.2–8.0

0.001

IgE, cat dander

34 (32 %)

22.7–40.2

17 (8 %)

4.3–11.5

0.001

IgE, cockroach

29 (27 %)

18.5–35.2

28 (13 %)

8.5–17.4

0.001

IgE, dust mite

40 (37 %)

27.9–46.1

39 (18 %)

12.9–23.2

0.001

IgE, dog dander

30 (28 %)

19.3–36.2

13 (6 %)

2.8–9.2

0.001

> one antigen over detection limit

66 (61 %)

51.9–70.3

61 (28 %)

22.2–34.2

0.001

History of hay fever or seasonal allergy

38 (36 %)

26.2–44.2

65 (32 %)

24.0–36.2

0.444

  1. apolymorphonuclear leukocytes
  2. btotal Immunoglobulin E
  3. cantigen specific IgE (ie above minimum detection limit, <0.35 kUA/L)