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Table 2 Vitamin D related molecules in Pleural effusion

From: Vitamin D nutritional status and vitamin D regulated antimicrobial peptides in serum and pleural fluid of patients with infectious and noninfectious pleural effusions

Parameter

IE

ME

CHFE

P Value

Exudate

Transud.

P Value

CIE

NCIE

P Value

25OH Vitamin D (ng/mL)

Serum

12 (5, 84)

18.4 (6.9, 41)

10,4 (3, 39.6)

0,001

12.8 (5, 84)

10.6 (3, 39,6)

0,019

11.85 (9.2, 16.2)

13.5 (7.6, 22.4)

0.731

 

Pleura

16 (1, 63)

17 (5.5, 47)

12.2 (1, 30.5

0,016

15 (1, 63)

12 (1, 25)

0,048

16 (9.65, 20.65)

15 (7.75, 25.32)

0.551

1,25 (OH)2 Vitamin D (pg/mL)

Serum

25.65 (7, 113)

46 (9, 140)

22.5 (5, 116)

0,043

25.65 (5, 140)

22 (8, 66)

0,708

22 (14.5, 35.5)

32 (8.5, 41.5)

0.751

 

Pleura

22 (4, 132)

31.5 (0.4, 1.28)

12 (2, 52)

0,001

18 (4, 132)

12 (2, 50)

0,030

22 (12, 34)

21.5 (7.2, 32.5)

0.627

VDBP (mg/L)

Serum

203 (29, 494)

275.10 (13.13, 730)

197 (27, 1122)

0,1

236 (13, 730

190 (27, 1122)

0,307

139 (29, 285)

166 (42, 338)

0.71

 

Pleura

134 (4, 834)

191 (5, 464)

95 (10, 446)

0,001

155 (4, 834)

95 (10, 446)

0,48

85 (10, 183)

217 (30, 258)

0.112

LL-37 (ng/mL)

Serum

0.84 (0.01, 153)

0.47 (0.01, 12.62)

0.25 (0.01, 10.34)

0.017

0.67 (0.01, 153)

0,.24 (0.01, 10.3)

0.017

0,51 (0.28, 1.29)

1.43 (0.95, 1.85)

0.029

 

Pleura

1.42 (0.05, 153)

0.52 (0.01, 13.51)

0.3 (0.01, 3.3)

0.001

0.91 (0.01, 153)

0.3 (0.01, 3.3)

0..001

1.05 (0.47, 4.28)

3.11 (1,62, 5.62)

0.014

β-defensin-2 (pg/mL)

Serum

232 (14, 2100)

224 (10, 3000)

284 (9, 1834

0.966

213 (9, 3000)

258 (9, 1834)

0.651

431 (136, 1015)

112 (71, 233)

0.023

 

Pleura

265.2 (6, 1293)

276 (25, 3000)

241 (5, 2206)

0.706

240 (6, 3000)

214 (5, 2206)

0.484

383 (72, 804)

152 (16, 352)

0.091

  1. IE Infectious effusions, CHFE Congestive heart failure effusions, ME Malignant effusions, CIE Complicated infectious effusions, NCIE Non complicated infectious effusions, WBC White blood cells, N Neutrophils, LDH Lactate Dehydrogenase, VDBP Vitamin D Binding Protein, LL-37 Leucin leucin 37 (Cathelicidin). Data presented as mean ± SD for parametric results and mean (interquartilic range)