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Table 3 Parameters at baseline according to exercise-induced oxygen desaturation during 6MWT

From: Heart rate response during 6-minute walking testing predicts outcome in operable chronic thromboembolic pulmonary hypertension

  Baseline  
  EID Non-EID p-value
Patients, n (%) 12 (32.4) 25 (67.6)  
WHO functional class, (%) a 0.09
 II 33.3 24  
 III 41.7 72  
 IV 25 4  
6MWT    
 6MWD (m) 448.9 ± 206.8 383.6 ± 109.5 0.22
 Rest SpO2 (%) 92.0 ± 2.2 94.8 ± 2.1 0.002
 Peak SpO2 (%) 81.9 ± 4.4 92.1 ± 2.3 0.001
 Δ SpO2 (%) 10.0 ± 1.1 2.7 ± 0.4 0.02
 Rest HR (beatsamin-1) 83.5 ± 16.4 84 ± 13.7 0.9
 Peak HR (beatsamin-1) 120.6 ± 20.7 115.5 ± 18.1 0.45
 Δ HR (beatsamin-1) 30.5 ± 5.1 30.4 ± 2.4 0.82
 HRR (%) 49.5 ± 8.1 42.5 ± 4 0.53
 Δ Borg 4.7 ± 0.7 4.3 ± 0.5 0.52
 Supplemental Oxygen (n, %) 4 (33.3) 5 (20) a 0.38
Lung function    
 FEV1 (% pred.) 83.6 ± 11.9 90.9 ± 14.1 0.15
 FEV1/FVC (% pred.) 98.6 ± 10.2 94.8 ± 10.3 0.31
 TLC (% pred.) 94.8 ± 16.3 100.8 ± 12.1 0.24
 VC (% pred.) 85.8 ± 10.3 94.1 ± 14.4 0.1
RHC   
 mPAP (mm Hg) 43.8 ± 8.2 42.9 ± 9.0 0.77
 RAP (mm Hg) 4.1 ± 2.7 6.6 ± 4.4 0.8
 PVR (dyneas/cm5) 640.1 ± 231.0 587.4 ± 230.5 0.53
 CI (l/min/m2) 2.5 ± 0.6 2.4 ± 0.5 0.7
 PAWP (mm Hg) 9.3 ± 2.8 9.7 ± 5.4 0.8
Echocardiography   
 TAPSE (mm) 16.6 ± 4.3 17.4 ± 4.3 0.63
 PASP (mm Hg) 77.2 ± 30.7 66.2 ± 21.7 0.24
CPETc    
 Peak VO2 (ml/min/kg) 13.1 ± 1.3 12.1 ± 0.6 0.65
 Rest VD/VT 33.0 ± 7.3 36.0 ± 8 0.48
 Peak VD/VT 39.0 ± 12.0 40.0 ± 7.3 0.78
 Rest VD, L 0.41 ± 0.22 0.34 ± 0.14 0.4
 Peak VD, L 0.67 ± 0.33 0.65 ± 0.23 0.9
Jamieson-Type, (%) a 0.72
 I 25 32  
 II 50 26  
 III 25 42  
Laboratory   
 NT-proBNP (pg/ml) 414.0 [1260.2] 836.7 [1521]b 0.71
  1. Values represent mean ± SD or median [IQR]. a = Pearson Chi-Square test, b = Mann-Whitney U Test, cn = 34.; For abbreviations see Table 1