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Table 4 Baseline parameters as predictors of residual PH 1 year post PEA

From: Heart rate response during 6-minute walking testing predicts outcome in operable chronic thromboembolic pulmonary hypertension

 

Univariate model

Multivariate model*

 

Hazard ratio (95 % confidence interval)

p-value

Hazard ratio (95 % confidence interval)

p-value

6MWT

    

 6MWD (m)

1.01 [0.99–1.01]

0.44

-

-

 Rest SpO2 (%)

1.25 [0.94–1.67]

0.11

-

-

 Peak SpO2 (%)

0.96 [0.85–1.08]

0.46

-

-

 Δ SpO2 (%)

0.99 [0.86–1.16]

0.96

-

-

 Rest HR (beats*min-1)

0.99 [0.94–1.03]

0.6

-

-

 Peak HR (beats*min-1)

1.03 [0.99–1.06]

0.19

-

-

 Δ HR (beats*min-1)

1.10 [1.03–1.2]

0.009

-

-

 HRR (%)

1.06 [1.02–1.1]

0.01

1.06 [0.99–1.14]

0.08

CPET

    

 Rest SpO2 (%)

1.81 [0.86–3.76]

0.12

-

-

 Peak SpO2 (%)

1.02 [0.86–1.20]

0.84

-

-

 Δ SpO2 (%)

1.05 [0.86–1.27]

0.66

-

-

 Rest HR (beats*min-1)

0.96 [0.90–1.02]

0.16

-

-

 Peak HR (beats*min-1)

0.98 [0.95–1.01]

0.25

-

-

 Δ HR (beats*min-1)

0.99 [0.96–1.03]

0.71

-

-

 HRR (%)

1.00 [0.97–1.03]

0.91

-

-

 Peak VO2 (ml/min/kg)

0.95 [0.78–1.17]

0.63

-

-

RHC

    

 mPAP (mm Hg)

1.07 [0.98–1.16]

0.13

-

-

 RAP (mm Hg)

1.01 [0.83–1.2]

0.96

-

-

 PVR (dyne*s/cm5)

1.01 [0.99–1.01]

0.19

-

-

 CI (l/min/m2)

1.10 [0.3–4.01]

0.89

-

-

 PAWP (mm Hg)

1.03 [0.89–1.2]

0.67

-

-

Echocardiography

    

 TAPSE (mm)

0.90 [0.77–1.06]

0.2

-

-

 PASP (mm Hg)

1.03 [0.99–1.07]

0.06

-

-

Other

    

 Nt-pro BNP (pg/ml)

1.00 [0.99–1.01]

0.97

-

-

 WHO functional class

-

0.39

-

-

Jamieson-Type

    

 • I

Reference

 

Reference

 

 • II

4.2 [0.6–30.1]

0.15

8.9 [0.7–116.4]

0.096

 • III

1.67 [0.28–3.57]

0.58

5.02 [3.23–100]

0.25

  1. For abbreviations see Table 1. *: backward stepwise logistic regression including variables with a p-value <0.15 in the univariate model