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Table 4 Baseline parameters as predictors of residual PH 1 year post PEA

From: Heart rate response during 6-minute walking testing predicts outcome in operable chronic thromboembolic pulmonary hypertension

  Univariate model Multivariate model*
  Hazard ratio (95 % confidence interval) p-value Hazard ratio (95 % confidence interval) p-value
6MWT     
 6MWD (m) 1.01 [0.99–1.01] 0.44 - -
 Rest SpO2 (%) 1.25 [0.94–1.67] 0.11 - -
 Peak SpO2 (%) 0.96 [0.85–1.08] 0.46 - -
 Δ SpO2 (%) 0.99 [0.86–1.16] 0.96 - -
 Rest HR (beats*min-1) 0.99 [0.94–1.03] 0.6 - -
 Peak HR (beats*min-1) 1.03 [0.99–1.06] 0.19 - -
 Δ HR (beats*min-1) 1.10 [1.03–1.2] 0.009 - -
 HRR (%) 1.06 [1.02–1.1] 0.01 1.06 [0.99–1.14] 0.08
CPET     
 Rest SpO2 (%) 1.81 [0.86–3.76] 0.12 - -
 Peak SpO2 (%) 1.02 [0.86–1.20] 0.84 - -
 Δ SpO2 (%) 1.05 [0.86–1.27] 0.66 - -
 Rest HR (beats*min-1) 0.96 [0.90–1.02] 0.16 - -
 Peak HR (beats*min-1) 0.98 [0.95–1.01] 0.25 - -
 Δ HR (beats*min-1) 0.99 [0.96–1.03] 0.71 - -
 HRR (%) 1.00 [0.97–1.03] 0.91 - -
 Peak VO2 (ml/min/kg) 0.95 [0.78–1.17] 0.63 - -
RHC     
 mPAP (mm Hg) 1.07 [0.98–1.16] 0.13 - -
 RAP (mm Hg) 1.01 [0.83–1.2] 0.96 - -
 PVR (dyne*s/cm5) 1.01 [0.99–1.01] 0.19 - -
 CI (l/min/m2) 1.10 [0.3–4.01] 0.89 - -
 PAWP (mm Hg) 1.03 [0.89–1.2] 0.67 - -
Echocardiography     
 TAPSE (mm) 0.90 [0.77–1.06] 0.2 - -
 PASP (mm Hg) 1.03 [0.99–1.07] 0.06 - -
Other     
 Nt-pro BNP (pg/ml) 1.00 [0.99–1.01] 0.97 - -
 WHO functional class - 0.39 - -
Jamieson-Type     
 • I Reference   Reference  
 • II 4.2 [0.6–30.1] 0.15 8.9 [0.7–116.4] 0.096
 • III 1.67 [0.28–3.57] 0.58 5.02 [3.23–100] 0.25
  1. For abbreviations see Table 1. *: backward stepwise logistic regression including variables with a p-value <0.15 in the univariate model