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Table 1 Demographic, clinical, and laboratory variables in 110 children hospitalized for radiologically confirmed community-acquired pneumonia according to their infection status

From: Measurement of lipocalin-2 and syndecan-4 levels to differentiate bacterial from viral infection in children with community-acquired pneumonia

 

All subjects

Probable bacterial

Probable viral

Undetermined

 

n = 110

n = 74

n = 16

n = 20

Demographics and clinical presentation

 Males (%)

61 (55.4)

45 (60.8)*

5 (31.2)*

11 (55.0)

 Mean age ± SD (years)

4.8 ± 3.4

5.1 ± 3.4

3.6 ± 2.8

4.9 ± 3.5

 Caucasians (%)a

95 (88.8)

62 (87.3)

13 (81.2)

20 (100.0)

 At least one parent smoked (%)a

28 (25.9)

19 (26.0)

5 (31.2)

4 (21.0)

 Presence of fever” (%)

91 (82.7)

64 (86.5)

12 (75.0)

15 (75.0)

 O2 therapy (%)a

26 (25.2)

14 (19.7)*

7 (50.0)*

5 (27.8)

 Clinical findings (%)

  Rhonchi

12 (10.9)

5 (6.8)

3 (18.7)

4 (20.0)

  Rales

92 (83.6)

63 (85.1)

14 (87.5)

15 (75.0)

  Wheezing

21 (19.1)

11 (14.9)

3 (18.7)

7 (35.0)

  Any of the above

96 (87.3)

64 (86.5)

15 (93.7)

17 (85.0)

 Severe disease

84 (76.4)

59 (79.7)

12 (75.0)

13 (65.0)

Laboratory data

 WBC (cells/μL)a

15,741 ± 8,575

16,573 ± 8,969

13,674 ± 7338

14,358 ± 7,899

  Neutrophils, %a

66.1 ± 19.3

68.3 ± 18.4

65.2 ± 17.8

59.2 ± 22.9

 CRP, μg/dLa

25.5 ± 47.4

32.2 ± 55.5*

9.4 ± 17.0*

14.0 ± 19.4

 LIP2, ng/mL

2,079 ± 1,606

2,158 ± 1,744

1,880 ± 1,015

1,946 ± 1,488

 SYD4, ng/mL

5.08 ± 3.95

5.27 ± 4.10

4.31 ± 3.06

4.99 ± 4.14

  1. CRP C-reactive protein, LIP2 lipocalin-2, SD standard deviation, SYD4 syndecan-4, WBC white blood cell count
  2. *p < 0.05 between probable bacterial and probable viral infection groups. No other statistically significant differences between groups were observed
  3. aSome missing values (two cases in probable bacterial CAP, two in probable viral CAP and two in undetermined CAP)