Table 1 Patient demographics and clinical information (N = 53)
Characteristics | |
|---|---|
Age (years) | 65 (35–85) |
Gender | |
Male | 19 (35.9) |
Female | 34 (64.1) |
ECOG PS | |
0 | 23 (43.4) |
1 | 27 (50.9) |
2 | 2 (3.8) |
3 | 1 (1.9) |
4 | 0 (0) |
Histologic diagnosis | |
Adenocarcinoma | 52 (98.1) |
Adenosquamous cell carcinoma | 1 (1.9) |
Initial EGFR mutation profile | |
Del19 | 30 (56.6) |
L858R | 22 (41.5) |
L816Q | 1 (1.9) |
EGFR-TKI treatment before re-biopsy | |
Gefitinib | 29 (54.8) |
Erlotinib | 7 (13.2) |
Afatinib | 0 (0) |
Gefitinib + Erlotinib | 12 (22.6) |
Gefitinib + Afatinib | 1 (1.9) |
Gefitinib + Erlotinib + Afatinib | 4 (7.5) |