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Table 4 Factors associating with the differential course of disease in the patients with rheumatoid arthritis associated usual interstitial pattern (RA-UIP) and non-UIP patterns (RA-non-UIP)

From: Variable course of disease of rheumatoid arthritis-associated usual interstitial pneumonia compared to other subtypes

Factor

RA-ILD

RA-UIP

RA-non-UIP

P-value

(n = 59)

(n = 35, 59.3 %)

(n = 24, 40.7 %)

Oxygen therapy

8 (13.6)

8 (22.9)

0 (0)

0.016

Hospitalization due to respiratory illness

1.29 ± 2.2 (0–11)

1.9 ± 2.6 (0–11)

0.5 ± 0.9 (0–4)

0.004

Hospitalization due to cardiac illness

0.6 ± 1.2 (0–5)

0.7 ± 1.3 (0–5)

0.4 ± 1.2 (0–4)

0.100

Latest FVC % pred

82 ± 21.2

78 ± 22.9

87 ± 17.2

0.091

(Baseline FVC %)

85 ± 17.0

82 ± 17.1

89 ± 16.5

 

Latest DLCO % pred

61 ± 21.3

56 ± 20.6

69 ± 20.2

0.021

(Baseline DLCO %)

71 ± 18.1

72 ± 20.7

70 ± 13.3

 

Number of deaths

33 (55.9)

23 (65.7)

9 (37.5)a

0.046

  1. Data are presented as percentage or mean ± SD and also (range) in hospitalization
  2. Hospitalization comparison performed using Mann–Whitney U-test and the lung function comparison using an independent sample T-test
  3. aOne RA-DAD-patient is excluded from this group, P-value calculation and survival analyses