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Table 1 Classification of patients by asthma severity adapted from EPR-3 step-treatment recommendations

From: Value of peripheral blood eosinophil markers to predict severity of asthma

Severity

EPR-3 Step-Treatment Recommendations

Mild

• Low dose ICS, or

• Cromolyn, LTRA, Nedocromil, or Theophylline

Moderate-to-severe

• Low-dose ICS + LABA OR Medium-dose ICS OR Medium-dose ICS + LABA, or

• Low-dose ICS + either LTRA, Theophylline, or Zileuton, or

• Medium-dose ICS + either LTRA, Theophylline, or Zileuton

• High-dose ICS + LABA OR High-dose ICS + LABA + oral corticosteroid,or

• High-dose ICS + LABA + _Omalizumab, or High-dose ICS + LABA + oral corticosteroid + Omalizumab, or

• Omalizumab