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Table 3 TLR2 SNP Genotypes and Minor Allele Frequencies (MAF) along with Hardy Weinberg Equilibrium Values in Asthmatic and Control Groups

From: A case–control study of innate immunity pathway gene polymorphisms in Puerto Ricans reveals association of toll-like receptor 2 +596 variant with asthma

SNP Genotypes

Asthmatics N (%)

Controls N (%)

Total N (%)

Hardy Weinberg Equilibrium (X2, p > 0.05)

TLR2 +596

   

0.14

 CC

7 (11.3)

17 (27.9)

24 (19.5)

 CT

36 (58.1)

27 (44.3)

63 (51.2)

 TT

19 (30.6)

17 (27.8)

36 (29.3)

 MAF (C)

0.35 (35)

0.36 (36)

 

TLR2 -16934

   

0.65

 TT

17 (27.4)

14 (23.0)

31 (25.2)

 AT

32 (51.6)

26 (42.6)

58 (47.2)

 AA

13 (21.0)

21 (34 .4)

34 (27.6)

 MAF (A)

0.35 (35)

0.38 (38)

 

TLR2 +399

   

0.88

 AA

23 (37.1)

29 (47.5)

52 (42.3)

 AG

33 (53.2)

26 (42.6)

59 (48.0)

 GG

6 (9.7)

6 (9.8)

12 (9.7)

 MAF (G)

0.32 (32)

0.26 (26)

 

TLR2 +1349

   

2.53

 TT

56 (90.3)

57 (93.4)

113 (91.9)

 CT

6 (9.7)

3 (4.9)

9 (7.3)

 CC

0

1 (1.6)

1 (0.8)

 MAF (C)

0.05 (5)

0.03 (3)

 
  1. Hardy Weinberg equilibrium chi-square values were acquired under a p-value >0.05