From: Aspergillus nodules; another presentation of Chronic Pulmonary Aspergillosis
Patient | Number of nodules | Lobes of lung involved | Min size (mm) | Max size (mm) | Lymphadenopathy | Visible on concurrent CXR | Symptoms | Aspergillus IgG | Sputum culture | Aspergillus PCR | Tissue Specimen | Results |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspergillus Nodules | ||||||||||||
1 | 1 | LLL | 11 | N | Y | None | 76 | n/a | lung | fibrosis, fungal hyphae | ||
2 | 2 | Upper lobes bilaterally | 4 | 10 | n | y | None | 68 | Negative | lung | granuloma, necrosis, fungal hyphae | |
3 | 1 | LUL | 16 | n | y | Dyspnoea, cough, weight loss | 14 | Negative | lung | Inflammation, fungal hyphae | ||
4 | 2 | RUL | 7 | n | y | Cough, weight loss | 40 | Negative | Lung | Inflammation granulomatous | ||
5 | 1 | RUL | 16 | n | y | Dyspnoea, weight loss | 101 | n/a | lung | COP, fungal hyphae | ||
6 | 1 | RUL | 12 | n | y | Dyspnoea, cough, haemoptysis | N/A | A. fumigatus | n/a | BAL | inflammatory infiltrate fungal hyphae | |
7 | 1 | LUL | 22 | n | y | Dyspnoea, cough | 22 | N/A | lung | fibrosis, granulomata, necrosis, fungal hyphae | ||
8 | 1 | RUL | 22 | n | y | Dyspnoea, cough, haemoptysis | 86 | Negative | lung | Inflammation, fungal hyphae | ||
9 | 3 | Upper lobes bilaterally | 6 | 27 | n | y | Dyspnoea, cough, weight loss | 54 | A. fumigatus | Negative | lung | fungal hyphae, necrosis |
10 | 1 | LLL | 25 | could not visualise | y | Dyspnoea, cough | 23 | A. fumigatus | Positive | Lung | Inflammation granulomatous | |
11 | 2 | LUL | 9 | 35 | n | y | Dyspnoea, cough | 32 | Weak positive | Lung | Inflammation granulomatous | |
Probable Aspergillus Nodules | ||||||||||||
12 | 4 | All lobes | 2 | 38 | y | y | Dyspnoea, cough, haemoptysis | 185 | Positive | |||
13 | 2 | Upper lobes bilaterally | 3 | 9 | n | N/A | Cough | 87 | Negative | |||
14 | 4 | All lobes except RUL | 2 | 16 | n | y | Dyspnoea, cough | 49 | n/a | BAL | benign cells, polymorphs | |
15 | 2 | Upper lobes bilaterally | 7 | 12 | y | y | Dyspnoea, cough | 68 | Negative | |||
16 | 4 | all lobes except RML | 5 | 16 | n | Y | Dyspnoea, cough | 65 | A. nidulans, A. niger | Negative | ||
17 | 1 | LUL | 14 | n | Y | Dyspnoea, cough, weight loss | 152 | N/A | BAL | benign cells, polymorphs | ||
18 | 1 | RUL | 10 | n | y | Cough, weight loss | 18 | n/a | ||||
19 | 4 | All lobes | 2 | 31 | Y | Y | Dyspnoea, cough, haemoptysis, weight loss | 52 | A. fumigatus | Weak positive | lung | haemosiderin deposition |
20 | 4 | Upper lobes bilaterally | 1 | 13 | y | y | Dyspnoea, cough | 190 | A. fumigatus | Weak positive | lung | inflammatory debris |
21 | 4 | All lobes except RUL | 1 | 18 | n | y | Dyspnoea, cough | 115 | A fumigatus | Positive | ||
22 | 1 | LUL | 16 | n | y | Dyspnoea, cough, weight loss | 19 | A nidulans, A.fumigatus | Weak positive | ` | ||
23 | 4 | All lobes | 1 | 16 | y | n | Dyspnoea, cough | 75 | N/A | Lung | Emphysema bullous | |
24 | 1 | RUL | 20 | n | y | Cough | 12 | A. fumigatuis | N/A | |||
25 | 4 | All lobes | 1 | 20 | y | Y | Cough | 170 | Negative | |||
26 | 4 | All lobes | 5 | 34 | n | Dyspnoea, cough, weight loss | 104 | Weak positive | ||||
27 | 4 | All lobes | 1 | 5 | n | y | Dyspnoea, cough | 42 | A. fumigatus | Positive | ||
28 | 4 | RUL | 1 | 27 | n | y | Cough, haemoptysis | 82 | Positive | |||
29 | 4 | all except RML, RLL | 1 | 28 | N | Y | Dyspnoea | 42.5 | N/A | |||
30 | 3 | LUL | 5 | 37 | n | y | Cough | 106 | Negative | |||
31 | 1 | RUL | 29 | n | y | Cough | 18 | Negative | ||||
32 | 4 | All lobes | 6 | 32 | n | y | Dyspnoea, cough, weight loss | 10 | N/A | |||
33 | 2 | LUL | 17 | 50 | n | N/A | Dyspnoea, cough, weight loss | 108 | Negative |