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Table 1 Characteristic of patients diagnosed with Aspergillus nodule(s)

From: Aspergillus nodules; another presentation of Chronic Pulmonary Aspergillosis

Patient

Number of nodules

Lobes of lung involved

Min size (mm)

Max size (mm)

Lymphadenopathy

Visible on concurrent CXR

Symptoms

Aspergillus IgG

Sputum culture

Aspergillus PCR

Tissue Specimen

Results

Aspergillus Nodules

            

 1

1

LLL

 

11

N

Y

None

76

 

n/a

lung

fibrosis, fungal hyphae

 2

2

Upper lobes bilaterally

4

10

n

y

None

68

 

Negative

lung

granuloma, necrosis, fungal hyphae

 3

1

LUL

 

16

n

y

Dyspnoea, cough, weight loss

14

 

Negative

lung

Inflammation, fungal hyphae

 4

2

RUL

 

7

n

y

Cough, weight loss

40

 

Negative

Lung

Inflammation granulomatous

 5

1

RUL

 

16

n

y

Dyspnoea, weight loss

101

 

n/a

lung

COP, fungal hyphae

 6

1

RUL

 

12

n

y

Dyspnoea, cough, haemoptysis

N/A

A. fumigatus

n/a

BAL

inflammatory infiltrate fungal hyphae

 7

1

LUL

 

22

n

y

Dyspnoea, cough

22

 

N/A

lung

fibrosis, granulomata, necrosis, fungal hyphae

 8

1

RUL

 

22

n

y

Dyspnoea, cough, haemoptysis

86

 

Negative

lung

Inflammation, fungal hyphae

 9

3

Upper lobes bilaterally

6

27

n

y

Dyspnoea, cough, weight loss

54

A. fumigatus

Negative

lung

fungal hyphae, necrosis

 10

1

LLL

 

25

could not visualise

y

Dyspnoea, cough

23

A. fumigatus

Positive

Lung

Inflammation granulomatous

 11

2

LUL

9

35

n

y

Dyspnoea, cough

32

 

Weak positive

Lung

Inflammation granulomatous

Probable Aspergillus Nodules

            

 12

4

All lobes

2

38

y

y

Dyspnoea, cough, haemoptysis

185

 

Positive

  

 13

2

Upper lobes bilaterally

3

9

n

N/A

Cough

87

 

Negative

  

 14

4

All lobes except RUL

2

16

n

y

Dyspnoea, cough

49

 

n/a

BAL

benign cells, polymorphs

 15

2

Upper lobes bilaterally

7

12

y

y

Dyspnoea, cough

68

 

Negative

  

 16

4

all lobes except RML

5

16

n

Y

Dyspnoea, cough

65

A. nidulans, A. niger

Negative

  

 17

1

LUL

 

14

n

Y

Dyspnoea, cough, weight loss

152

 

N/A

BAL

benign cells, polymorphs

 18

1

RUL

 

10

n

y

Cough, weight loss

18

 

n/a

  

 19

4

All lobes

2

31

Y

Y

Dyspnoea, cough, haemoptysis, weight loss

52

A. fumigatus

Weak positive

lung

haemosiderin deposition

 20

4

Upper lobes bilaterally

1

13

y

y

Dyspnoea, cough

190

A. fumigatus

Weak positive

lung

inflammatory debris

 21

4

All lobes except RUL

1

18

n

y

Dyspnoea, cough

115

A fumigatus

Positive

  

 22

1

LUL

 

16

n

y

Dyspnoea, cough, weight loss

19

A nidulans, A.fumigatus

Weak positive

 

`

 23

4

All lobes

1

16

y

n

Dyspnoea, cough

75

 

N/A

Lung

Emphysema bullous

 24

1

RUL

 

20

n

y

Cough

12

A. fumigatuis

N/A

  

 25

4

All lobes

1

20

y

Y

Cough

170

 

Negative

  

 26

4

All lobes

5

34

n

 

Dyspnoea, cough, weight loss

104

 

Weak positive

  

 27

4

All lobes

1

5

n

y

Dyspnoea, cough

42

A. fumigatus

Positive

  

 28

4

RUL

1

27

n

y

Cough, haemoptysis

82

 

Positive

  

 29

4

all except RML, RLL

1

28

N

Y

Dyspnoea

42.5

 

N/A

  

 30

3

LUL

5

37

n

y

Cough

106

 

Negative

  

 31

1

RUL

 

29

n

y

Cough

18

 

Negative

  

 32

4

All lobes

6

32

n

y

Dyspnoea, cough, weight loss

10

 

N/A

  

 33

2

LUL

17

50

n

N/A

Dyspnoea, cough, weight loss

108

 

Negative