Table 4 Overall drop-out rate and main reasons for treatment discontinuation in the NEONet database
Patient population (n = 221) | Drop-out patients (70, 32 %) | Patients under treatment (151, 38 %) | p-value |
|---|---|---|---|
Males, n (%) | 25 (35.71) | 68 (45.03) | 0.0959 |
Females, n (%) | 45 (64.29) | 83 (54.97) | |
Age-years, mean (SD) | 46.79 (14.82) | 47.44 (13.11) | 0.4904 |
Treatment duration-months, mean (SD) | 27.69 (20.94) | 27.54 (22.96) | 0.4992 |
Reason for drop-out, n (%) | |||
Lack of efficacy | 18 (26) | Â | Â |
Patient’s decision discontinuation | 34 (49) |  |  |
Efficacy | 4 (6) | Â | Â |
Adverse events (local or systemic reactions) | 5 (7) | Â | Â |
Onset of contraindications | 6 (8) | Â | Â |
Patient moved to another referral center | 3 (4) | Â | Â |