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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: Baicalin attenuates bleomycin-induced pulmonary fibrosis via adenosine A2a receptor related TGF-β1-induced ERK1/2 signaling pathway

Fig. 2

A2aR and baicalin alleviated pulmonary histopathological changes in the BLM mouse model. a Images of H&E of pulmonary tissue sections (light microscopy, ×400). Control groups show the normal interalveolar septum; model groups indicate widespread interalveolar septum thickness; baicalin groups exhibit reduced tissue injury. And the histopathological changes in KO mice are more obvious. b Images of Masson’s trichrome staining of pulmonary tissue sections (light microscopy, ×400). Control groups show no obvious collagen fibers deposition; model groups indicate an abundance of collagen deposition (blue-stained); baicalin groups exhibit reduced collagen fibers deposition. The deposition of collagen fibers in KO mice is more obvious. Scale bars represent 100 μm

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