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Table 2 Comparison of ACQ and ACT scores, rescue medication use, days free of symptoms, and lung function parameters

From: Can severe asthmatic patients achieve asthma control? A systematic approach in patients with difficult to control asthma followed in a specialized clinic

Group (n)

NC (38)

C (13)

B

W2

W12

B

W2

W12

ACQ

3.43 ± 1.14

2.54 ± 1.11a

2.62 ± 0.75 b

2.8 ± 1.06

1.50 ± 0.76* a

0.92 ± 0.22* b

ACT§

10 (7 – 14)

13 (10 – 14)

13 (12 – 15)

13 (8 – 16)

17 (13 -– 20)* a

21 (19 – 23)* b

Rescue medication (puff/day) §

3.1 (1.1 – 5.3)

2.5 (1.3 – 4.2) a

2.2 (1.0 – 3.4) b

2.7 (1.0 – 6.3)

1.0 (0.2 – 3.0) a

0.4 (0 – 2.3)* b

Days free of symptoms (%)§

0 (0 – 21)

7 (0 – 33)

0 (0 – 33)

0 (0 – 20)

42 (20 – 84)* a

92 (22 – 100)* b

FVC (%)

66.8 ± 17.9

76.5 ± 21.3 a

69.5 ± 20.4

68.2 ± 23.3

82.3 ± 15.9 a

83.3 ± 18.5* b

FEV1 (%)

49.8 ± 17.3

65.4 ± 22.4a

55.2 ± 19.3b

54.8 ± 19.6

70.7 ± 18.6 a

70.0 ± 21.8* b

FEV1/FVC

65 ± 13

65 ± 22

68 ± 13

60 ± 12

70 ± 18 a

70 ± 11 b

  1. FEV 1 forced expiratory volume in the first second, FVC forced vital capacity, NC non-controlled group, C controlled group, B baseline, W week
  2. *p < 0.05 (NC vs C); a p < 0.05 (W2 vs B); b p < 0.05 (W12 vs B); Mean ± SD; §median (IQR)