Table 1 Distribution of TnT by relevant covariates at baseline
Covariate | High sensitivity Troponin T, ng/L | p-value* | ||
|---|---|---|---|---|
<5.0 (n = 95) | 5.0–13.9 (n = 114) | ≥14.0 (n = 66) | ||
Age, years, mean (SD) | 62 (7.3) | 64 (6.7) | 67 (7.2) | <0.001 |
Female, n (%) | 64 (67) | 56 (49) | 26 (39) | <0.001 |
BMI, mean (SD) | 24.7 (5.1) | 24.7 (5.4) | 24.5 (5.4) | 0.962 |
GOLD class III/IV, n (%) | 46 (48) | 60 (53) | 51 (77) | 0.001 |
Hypertension, n (%) | 32 (34) | 36 (32) | 36 (55) | 0.006 |
Diabetes, n (%) | 4 (4) | 1 (1) | 9 (14) | 0.001 |
Current smoking, n (%) | 34 (36) | 29 (26) | 11 (17) | 0.025 |
Pack years, mean (SD) | 35 (16.1) | 35 (16.9) | 37 (19.5) | 0.686 |
Systolic BP, mmHg mean (SD) | 132 (21.9) | 138 (20.1) | 138 (19.5) | 0.080 |
Hemoglobin, g/dL mean (SD) | 14.1 (1.2) | 14.3 (1.1) | 15.7 (13.7) | 0.285 |
Heart rate per min, mean (SD) | 70 (13.3) | 71 (12.9) | 75 (13.9) | 0.067 |
LVH, n (%) | 1 (1) | 5 (5) | 2 (3) | 0.358 |
Pathologic Q-wave, n (%) | 5 (5) | 6 (5) | 9 (14) | 0.067 |
Use of antiplatelet therapy, n (%) | 10 (10) | 12 (11) | 5 (8) | 0.781 |
PaO2, kPa, mean (SD) | 9.0 (1.1) | 9.3 (1.3) | 8.9 (1.3) | 0.058 |
PaCO2, kPa, mean (SD) | 5.4 (0.7) | 5.4 (0.8) | 5.5 (0.8) | 0.847 |
Leucocytes, x109/L, mean (SD) | 7.0 (1.7) | 7.1 (1.9) | 7.8 (2.3) | 0.028 |
GFR, mL/min, mean (SD) | 89 (3) | 89 (3) | 79 (4) | 0.044 |
6MWD, meters, mean (SD) | 465 (109) | 455 (123) | 365 (104) | <0.001 |
mMRC >2, n (%) | 42 (44) | 58 (51) | 47 (71) | 0.003 |
AECOPD during last year, n (%) | 33 (35) | 40 (36) | 28 (43) | 0.571 |