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Table 2 Correlation between clinical signs and blood count with cytokines serum levels of patients with severe and non-severe pneumonia

From: The balance between the serum levels of IL-6 and IL-10 cytokines discriminates mild and severe acute pneumonia

  IL-12p70 TNF IL-10 IL-6 IL1β IL-8 IFN IL-17A IL5 IL-6/IL-10
  r P r P r P r P r P r P r P r P r P r P
Severe pneumonia
 Clinical signs (days)
  Abdominal pain 0.30 0.263 0.06 0.812 0.03 0.923 0.05 0.844 0.38 0.147 0.32 0.229 0.07 0.803 0.78 0.799 −0.37 0.150 0.04 0.897
  Sickness −0.03 0.906 −0.11 0.676 −0.09 0.742 0.03 0.902 −0.08 0.759 −0.12 0.661 −0.47 0.093 −0.42 0.153 −0.26 0.306 0.05 0.842
  Fever 0.33 0.208 0.25 0.359 0.28 0.293 0.46 0.073 0.35 0.190 −0.13 0.644 −0.29 0.315 −0.38 0.196 −0.36 0.155 0.43 0.097
  Anorexia −0.07 0.795 −0.04 0.874 −0.24 0.374 0.30 0.263 −0.43 0.097 −0.09 0.731 −0.26 0.377 −0.19 0.530 0.08 0.766 0.31 0.238
  Dyspnea −0.03 0.905 −0.02 0.945 −0.12 0.654 0.61 0.012 0.34 0.196 0.27 0.308 −0.09 0.761 −0.2 0.523 −0.39 0.126 0.62 0.010
  Subcostal recession 0.15 0.568 0.14 0.600 −0.14 0.605 0.03 0.918 0.36 0.166 −0.08 0.757 0.53 0.053 −0.15 0.615 −0.05 0.842 0.20 0.467
  Difficult breathing −0.10 0.715 0.09 0.736 −0.21 0.443 −0.05 0.862 0.09 0.738 0.23 0.388 −0.12 0.692 −0.17 0.581 0.18 0.484 −0.01 0.980
  Chest pain −0.18 0.518 0.01 0.971 −0.21 0.443 0.08 0.785 −0.12 0.676 −0.28 0.311 −0.23 0.454 −0.33 0.264 −0.03 0.912 −0.17 0.540
  Coughing −0.12 0.667 −0.02 0.532 −0.43 0.095 0.06 0.827 −0.44 0.090 −0.34 0.199 −0.39 0.165 −0.43 0.145 −0.35 0.167 0.11 0.688
  Vomiting −0.31 0.211 −0.24 0.376 0.16 0.549 0.58 0.019 −0.12 0.669 −0.08 0.761 0.22 0.447 0.28 0.362 −0.02 0.939 0.55 0.028
 Blood count
  Hemoglobin −0.06 0.814 −0.18 0.517 −0.16 0.556 0.18 0.516 −0.12 0.662 −0.62 0.011 −0.03 0.919 −0.25 0.417 −0.35 0.167 0.18 0.513
  Leukocytes −0.34 0.204 −0.25 0.357 −0.11 0.674 0.51 0.045 −0.08 0.779 −0.24 0.371 0.4 0.152 0.31 0.309 −0.28 0.277 0.52 0.037
  Hemacias −0.29 0.275 −0.41 0.114 −0.15 0.57 0.08 0.757 −0.27 0.306 −0.23 0.402 −0.07 0.809 −0.05 0.866 −0.44 0.081 0.08 0.762
  Neutrophils −0.09 0.753 −0.15 0.583 −0.25 0.351 0.43 0.1 −0.32 0.228 −0.37 0.164 −0.27 0.357 −0.29 0.346 −0.21 0.419 0.44 0.088
  Eosinophils −0.07 0.805 −0.09 0.755 −0.1 0.735 −0.13 0.639 0.23 0.413 −0.48 0.069 −0.18 0.552 −0.16 0.616 0.35 0.18 −0.10 0.720
  Lymphocytes 0.26 0.323 0.37 0.157 0.32 0.229 −0.33 0.218 0.45 0.084 0.46 0.071 0.32 0.268 0.31 0.307 0.4 0.114 −0.33 0.212
  Monocytes 0.34 0.204 0.56 0.025 0.32 0.223 −0.29 0.282 0.52 0.04 0.26 0.332 0.16 0.587 0.07 0.819 0.02 0.954 −0.29 0.279
  Platelets 0.01 0.963 0.11 0.673 −0.09 0.746 −0.21 0.431 −0.07 0.807 0.37 0.157 −0.02 0.955 0.06 0.84 0.42 0.09 −0.20 0.466
Non-severe Pneumonia
 Clinical signs (days)
  Abdominal pain 0.91 0.012 0.89 0.019 0.81 0.049 0.35 0.503 0.81 0.054 0.40 0.430 −0.38 0.534 −0.56 0.443 −0.38 0.406 0.34 0.514
  Sickness 0.29 0.579 0.29 0.287 0.41 0.418 −0.62 0.19 −0.30 0.569 −0.54 0.273 −0.31 0.612 −0.92 0.077 0.38 0.401 −0.62 0.185
  Fever 0.53 0.283 0.17 0.748 0.71 0.112 0.06 0.912 0.22 0.680 −0.06 0.909 0.11 0.856 0.10 0.897 −0.21 0.659 −0.17 0.745
  Anorexia −0.08 0.887 0.32 0.538 −0.02 0.975 0.36 0.479 0.57 0.237 0.30 0.561 −0.17 0.781 −0.28 0.722 −0.25 0.591 0.11 0.832
  Dyspnea −0.12 0.822 −0.23 0.658 0.19 0.722 −0.10 0.852 −0.18 0.739 −0.23 0.666 −0.24 0.693 −0.32 0.681 0.29 0.535 −0.11 0.837
  Subcostal recession - - - - - - - - - - - - - - - - - - - -
  Difficult breathing −0.13 0.809 0.32 0.543 −0.12 0.824 −0.19 0.371 0.18 0.739 −0.17 0.744 −0.38 0.534 −0.38 0.616 0.33 0.465 −0.20 0.707
  Chest pain - - - - - - - - - - - - −0.25 0.685 - - 0.28 0.550 - -
  Coughing 0.31 0.555 0.38 0.454 0.43 0.400 −0.48 0.340 −0.15 0.781 −0.39 0.450 −0.48 0.417 −0.95 0.046 0.46 0.300 −0.48 0.333
  Vomiting −0.09 0.884 0.13 0.839 −0.21 0.731 1.00 <0.001 0.73 0.164 0.99 0.001 - - - - −0.58 0.229 1.00 <0.001
 Blood count
  Hemoglobin 0.62 0.189 0.24 0.641 0.54 0.27 0.3 0.57 0.42 0.402 0.23 0.66 0.97 0.006 0.97 0.031 −0.82 0.024 0.29 0.575
  Leukocytes −0.55 0.256 −0.35 0.496 −0.68 0.138 0.49 0.328 0.16 0.765 0.44 0.387 0.54 0.348 0.72 0.282 −0.48 0.273 0.49 0.319
  Hemacias −0.45 0.371 −0.56 0.251 −0.65 0.166 0.29 0.571 −0.23 0.666 0.31 0.552 0.71 0.178 0.74 0.256 −0.49 0.268 0.31 0.551
  Neutrophils −0.64 0.172 −0.21 0.688 −0.76 0.078 0.49 0.321 0.2 0.699 0.5 0.311 −0.01 0.987 0.1 0.9 −0.18 0.707 0.50 0.313
  Eosinophils 0.49 0.325 0.19 0.714 0.71 0.113 −0.38 0.455 −0.13 0.813 −0.43 0.399 −0.31 0.61 −0.4 0.597 0.33 0.467 −0.39 0.440
  Lymphocytes 0.73 0.097 0.47 0.346 0.87 0.025 −0.48 0.333 −0.01 0.986 −0.47 0.345 −0.45 0.443 −0.62 0.379 0.3 0.516 −0.49 0.320
  Monocytes 0.08 0.888 −0.24 0.646 0.36 0.483 −0.44 0.386 −0.39 0.448 −0.56 0.247 0.02 0.98 −0.09 0.913 0.23 0.623 −0.45 0.374
  Platelets −0.42 0.411 −0.4 0.438 −0.34 0.506 −0.48 0.338 −0.71 0.115 −0.4 0.43 −0.39 0.519 −0.56 0.439 0.7 0.08 −0.47 0.346
  1. Note: r, Person correlation. P-value <0.05 was considered significant, significant values are shown in bold