Table 3 Interleukin (IL)-6 and the IL-6:IL-10 serum levels ratio as marker of pneumonia severity and recovery
IL-6 | IL-6/IL-10 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Time-points | Severe pneumonia | Non-severe pneumonia | CI 95% | Time-points | Severe pneumonia | Non-severe pneumonia | CI 95% | ||
At admission | Sen = 76.5 | 49.8 – 92.2 | At admission | Sen = 76.5 | 49.8 – 92.2 | ||||
>21.1 | 13 | 1 | Spec = 83.3 | 36.5 – 99.1 | >9.61 | 13 | 1 | Spec = 83.3 | 36.5 – 99.1 |
≤21.1 | 4 | 5 | PPV = 92.9 | 64.2 – 99.6 | ≤9.61 | 4 | 5 | PPV = 92.9 | 64.2 – 99.6 |
NPV = 55.6 | 22.7 – 84.7 | NPV = 55.6 | 22.7 – 84.7 | ||||||
D3 | Sen = 58.3 | 28.6 – 83.5 | D3 | Sen = 72.7 | 39.3 – 92.7 | ||||
>11.28 | 7 | 2 | Spec = 60.0 | 17.0 – 92.7 | >5.00 | 8 | 1 | Spec = 80.0 | 29.9 – 98.9 |
≤11.28 | 5 | 3 | PPV = 77.8 | 40.2 – 96.1 | ≤5.00 | 3 | 4 | PPV = 88.9 | 50.7 – 99.4 |
NPV = 37.5 | 10.2 – 74.1 | NPV = 57.1 | 20.2 – 88.2 | ||||||
D8 | D8 | ||||||||
>5.07 | 8 | 2 | Sen = 66.7 | 35.4 – 88.7 | >2.40 | 7 | 1 | Sen = 63.6 | 31.6 – 87.6 |
≤5.07 | 4 | 3 | Spec = 60.0 | 17.0 – 92.7 | ≤2.40 | 4 | 4 | Spec = 80.0 | 29.9 – 98.9 |
PPV = 80.0 | 44.2 – 96.5 | PPV = 87.5 | 46.7 – 99.3 | ||||||
NPV = 42.9 | 11.8 – 79.8 | NPV = 50.0 | 17.4 – 82.6 | ||||||