Table 1 Socio-demographic characteristics and disease severity across four symptom classes

 Age, years

68 ± 9

72 ± 9

68 ± 8

68 ± 8

64 ± 8

<.001^‡†§°^∞

 Females

59 (20%)

8 (10%)

10 (18%)

16 (21%)

25 (28%)

.04^§

 Education, some college+

234 (77%)

54 (68%)

48 (87%)

62 (81%)

70 (78%)

.05

 Income, > $20,000/year

184 (62%)

22 (29%)

16 (29%)

34 (44%)

43 (48%)

.02

 Live with others

223 (74%)

61 (76%)

39 (71%)

57 (74%)

66 (73%)

.92

 Currently smoking

86 (28%)

17 (21%)

19 (35%)

24 (31%)

26 (29%)

.35

 6-min walk test (feet)

1085 ± 371

1136 ± 370

1196 ± 310

984 ± 344

1061 ± 407

.005^∫

 FEV1% predicted

45.0 ± 15.8

48.1 ± 18.0

45.3 ± 14.6

42.0 ± 13.3

44.4 ± 16.2

.12

 O2 supplementation

100 (33%)

18 (23%)

11 (20%)

33 (43%)

38 (42%)

.002^†§∫°

 Number of co-morbidities

.39

  0

139 (46%)

37 (46%)

27 (49%)

30 (39%)

45 (50%)

  1

96 (32%)

30 (38%)

14 (25%)

25 (32%)

27 (30%)

  2 or more

67 (22%)

13 (16%)

14 (25%)

22 (29%)

18 (20%)

 Body mass index (BMI)

28.2 ± 6.1

27.8 ± 4.8

27.3 ± 5.1

29.5 ± 6.5

27.9 ± 7.1

.15

 Dyspnea, SOBQ (↓0–120)

42.4 ± 22.7

30.8 ± 18.2

22.1 ± 11.7

58.4 ± 16.8

51.5 ± 21.3

<.001^‡†§∫°

 Fatigue, CRQ (4–28↑)

15.8 ± 4.8

20.0 ± 3.6

19.2 ± 2.7

13.2 ± 3.1

12.3 ± 3.7

<.001^†§∫°

 Pain, SF-36 (0–100↑)

61.8 ± 24.3

74.2 ± 22.1

75.3 ± 22.7

52.1 ± 19.4

50.8 ± 21.7

<.001^†§∫°

 Anxiety, HAD-A (↓0–21)

5.0 ± 3.9

1.5 ± 1.3

4.7 ± 2.5

4.3 ± 2.6

8.9 ± 3.6

<.001^‡†§°^∞

 Depression, HAD-D (↓0–21)

4.2 ± 4.1

0.3 ± 0.5

3.2 ± 2.0

2.9 ± 1.7

9.4 ± 2.8

<.001^‡†§°^∞

 Depression history

<.001^†§

  None

101 (33%)

45 (56%)

19 (35%)

23 (30%)

14 (16%)

  First episode < = 40 y/o

137 (45%)

23 (29%)

25 (45%)

35 (45%)

54 (60%)

  First episode > 40 y/o

64 (21%)

12 (15%)

11 (20%)

19 (25%)

22 (24%)