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Table 5 Ebus sensitivity and negative predictive value according to FDG-PET results

From: FDG-PET parameters predicting mediastinal malignancy in lung cancer

  SUV Cut-off Tumor size n Mediastinal malignancyat EBUS EBUS-NA
Sensitivity
EBUS-NA
NPV
Mediastinal malignancy
at EUS-NA or mediastinoscopy
Mediastinal malignancy
at systematic nodal dissection
SUVmax mediastinum ≤4 ≤3 cm 22 4 (18.2%) 57.1% 83.3% 0 (0%) 3 (13.6%)
≤4 >3 cm 41 8 (19.5%) 61.5% 84.8% 1 (2,4%) 4 (9.7%)
>4 all 58 41 (70.7%) 87.2% 64.7% 5 (8.6%) 1 (1.7%)
\( \frac{\mathrm{SUVmax}\kern0.5em \mathrm{mediastinum}}{\mathrm{SUVmax}\kern0.62em \mathrm{tumor}} \) ≤0.4 ≤3 cm 15 4 (26.7%) 66.7% 81.8% 0 (0%) 2 (13.3%)
≤0.4 >3 cm 45 10 (22.2%) 76.9% 91.4% 1 (2.2%) 2 (2.2%)
>0.4 all 61 39 (63.9%) 84.8% 68.2% 5 (8.2%) 2 (3.3%)