Table 2 Correlates of natriuretic peptide in patients with COPD
From: B-type natriuretic peptides in chronic obstructive pulmonary disease: a systematic review
Study | n | Natriuretic peptide | FEV1 | PaO2 | Troponin | CRP | LVEF | PAP | RV dysfunction |
|---|---|---|---|---|---|---|---|---|---|
Echo | |||||||||
Anar [29] | 80 stable | NT–BNP | r = −0.06 p = 0.73 | r = −0.14 p = 0.40 | – | – | r = −0.22 p = 0.40 | r = 0.39p = 0.01 | RVD r = 0.36 p = 0.02 |
Bozkanat [28] | 38 stable | BNP | r = −0.65 p < 0.001 | r = −0.70 p < 0.001 | – | – | – | r = 0.68 p < 0.001 | – |
Chi [84] | 61 stable | NT–BNP | r = −0.56 p < 0.001 | r = −0.35 p = 0.03 | – | – | – | r = 0.44 p = 0.001 | – |
Hemlin [73] | 25 stable | BNP | – | – | – | – | – | r = 0.54 p = 0.02 | – |
Hwang [85] | 31 stable | NT–BNP | r = −0.26 p = ns | – | – | – | – | r = 0.59 p = 0.002 | – |
Inoue [35] | 60 stable | BNP | p = ns | p = ns | – | – | r = −0.41 p = 0.02 | r = 0.5 p = 0.004 | – |
Kim [75] | 22 stable | NT–BNP | p = ns | – | – | – | – | r = 0.51 p = 0.02 | – |
Mansour [86] | 57 stable | BNP | r = −0.49 p < 0.01 | r = −0.44 p < 0.05 | – | – | – | r = 0.49 p < 0.01 | – |
Ozdemirel [19] | 31 Stable | BNP | r = −0.44 p = 0.001 | – | – | – | – | r = 0.65 p = 0.02 | RVEF r = 0.09 p = 0.51 |
Kanat [31] | 37 AECOPD | BNP | – | p = ns | – | – | – | – | r = 0.474 p = 0.008 |
Lee [37] | 18 AECOPD | NT-BNP | – | – | – | – | r s  = −0.76 p < 0.001 | p = ns | TAPSE r s  = 0.51 p = 0.04 |
El Mallawany [39] | 20 AECOPD | NT–BNP | – | r = 0.19 p = 0.41 | – | r = 0.09 p = 0.71 | r = −0.58 p = 0.007 | – | – |
Nishimura [36] | 54 AECOPD | BNP | – | – | – | – | r s  = −0.22 p = 0.108 | – | – |
Ouanes [43] | 120 AECOPD | NT–BNP | – | – | – | – | r = −0.296 p = 0.008 | – | – |
Wang [32] | 311 AECOPD | NT–BNP | – | – | – | – | r = −0.35 p < 0.001 | r = 0.283 p < 0.001 | – |
No Echo | |||||||||
Chang [44] | 244 AECOPD | NT-BNP | – | p = ns | r s  = 0.46 p < 0.001 | r s  = 0.16 p = 0.01 | – | – | – |
Fujii [71] | 21 Stable | BNP | r = −0.30 p = ns | r = −0.39 p = ns | – | – | – | r = 0.28 p = ns | – |
Hoiseth [45] | 99 AECOPD | NT-BNP | – | – | r = 0.34 p = 0.0006 | – | – | – | – |
Martins [82] | 173 AECOPD | BNP | – | – | r = 0.06 p = 0.4 | – | – | – | – |
Patel [38] | 98 AECOPD | NT–BNP | – | – | r = 0.50 p < 0.001 | r = 0.46 p < 0.001 | – | – | – |
Stolz [33] | 208 AECOPD | BNP | r = 0.104 p = 0.222 | r = 0.115 p = 0.191 | – | r = 0.246 p = 0.001 | – | – | – |