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Table 1 Albuterol delivery in each configuration

From: Effects of ventilator settings, nebulizer and exhalation port position on albuterol delivery during non-invasive ventilation: an in-vitro study

 

Airway Pressure (cmH2O)

Albuterol delivery (% of dose)

 

Mode

EPAP or CPAP

IPAP

Config. A

Config. B

Config. C

Pairwise comparison (between configurations)

CPAP

5

-

12.5 ± 0.4

26.4 ± 3.6

37.0 ± 4.3

p < 0.001

10

-

11.5 ± 1.7

23.9 ± 1.5

32.8 ± 2.6

p < 0.001

BIPAP

5

10

9.5 ± 1.0

22.1 ± 3.5

30.9 ± 1.5

p < 0.001

5

15

13.5 ± 3.6*

27.7 ± 1.9*

35.1 ± 4.0*

p < 0.001

10

15

6.7 ± 0.4

25.2 ± 1.1

34.1 ± 3.6

p < 0.001

10

20

8.7 ± 0.9

25.7 ± 2.2

26.5 ± 6.1

p < 0.001

  1. CPAP, Continuous Positive Airway Pressure, BIPAP Bilevel Positive Airway Pressure, EPAP Expiratory Positive Airway Pressure, IPAP Inspiratory Positive Airway Pressure
  2. *Significantly higher compared to BIPAP 10/5 cmH2O and BIPAP 20/10 cmH2O (p < 0.05)