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Table 1 Reference algorithm used to capture COPD and asthma cases among the beneficiaries of the Regional Health Service. Lombardy, Italy

From: Can healthcare utilization data reliably capture cases of chronic respiratory diseases? a cross-sectional investigation in Italy

COPD Asthma
≥40 years of age
And at least one of the following criteria a :
≥1 hospitalizations for COPD
≥2 prescr/year of tiotropium or LABAs (in monotherapy),
LABA/ICS in fixed combinations, SABAs
≥2 prescr/year of ICS in addition to ≥2 prescr/year of
ipratropium or oxitropium
≥2 prescr/year of theophylline and ≥2 prescr/year of
any of the following drugs:beta-agonists, ipratropium, oxitropium, inhaled corticosteroids
<40 years of age
And at least one of the following criteria a :
Benefitted of exemption for asthma
≥1 hospitalizations for asthma
≥2 prescr/year of any of the following drugs: anti-leukotrienes, chromones,
≥2 prescr/year of any of the following drugs: SABAs, LABA/ICS fixed
combinations (only 0–19 age)
≥2 prescr/year of ICS in addition to ≥1 prescr/year of SABAs
≥2 prescr/year of ICS in addition to ≥2 prescr/year of ipratropium, oxitropium or
theophylline (only 0–19 age)
≥1 prescr/year of antibiotics (ATC: J01; only 20–39 age) in addition to at least
one of the following criteria:
≥2 prescr/year of theophylline and ≥2 prescr/year of any of the following drugs:
beta-agonists, ipratropium, oxitropium, inhaled corticosteroids
≥2 prescr/year of SABAs or LABA/ICS fixed combinations
≥2 prescr/year. of ICS in addition to ≥2 prescr/year of ipratropium or oxitropium
  1. To be recognized as affected by COPD/asthma, an individual must satisfy at least one of the listed criteria evaluated in 2010
  2. Abbreviations: prescr/yr. prescription per year
  3. aThe specific ATC, ICD-9 CM and exemption codes used to identify asthma and COPD cases are reported in Additional file 1: Table S1