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Table 2 Association between AWT Pi10 and pulmonary function parameters

From: Airway wall thickness on HRCT scans decreases with age and increases with smoking

 

AWT Pi10

b

p-value

FEV1 (L)

−1.697

0.001

FEF25–75 (L/s)

−3.215

0.001

FVC (L)

−1.288

0.047

FEV1/FVC (%)

−13.358

0.018

RV/TLC (%)

3.202

0.468

TLCOc/VA (mmol/min/kPa/L)

0.431

0.029

R5 (kPa/L/s)

0.363

<0.001

R20 (kPa/L/s)

0.288

<0.001

R5-20 (kPa/L/s)

0.075

0.164

X5 (kPa/L/s)

−0.080

0.028

  1. Linear regressions with pulmonary function parameters as outcome and airway wall thickness as predictor variable and age, gender, smoking status and height added as covariates
  2. AWT Pi10 airway wall thickness at an internal perimeter of 10 mm estimated from all measurements, FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, FEF 25–75 forced expiratory flow between 25 and 75% of FVC, RV/TLC residual volume/total lung capacity, TLCOc diffusion capacity of the lung for carbon monoxide, corrected for hemoglobin level, VA alveolar volume, R5 resistance at 5 Hz, R20 resistance at 20Hz, R5-20 difference between R5 and R20, X5 reactance at 5 Hz
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BMC Pulmonary Medicine

ISSN: 1471-2466

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