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Table 3 Key results of Recruitment Maneuvers in in silico ARDS patients with varying severity and cardiac output

From: Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome

 

Moderate ARDS, High CO [25]

Moderate ARDS, Normal CO [26]

Severe ARDS, High CO [27]

RM

MRS

SI

MRS

SI

MRS

SI

End RM PEEP, cm H2O

10

10

10

10

15

10

RecruitmentB (baseline), %

78

78

8

87

57

57

RecruitmentM (maximum), %

97

80

100

97

98

65.

R Ratio

19.59

2.50

13.00

10.31

41.84

12.31

∆ CO (at max PAW), l min−1

−2.3

−1.7

−1.6

−1.2

−2.3

−1.5

∆ RVEDV (at max PAW), ml

−14

−6

−55

−29

−18

−10

DO2 (baseline), ml min−1

1086

1086

754

754

902

902

∆ DO2 (at max PAW), ml min−1

810

834

453

540

697

689

∆ DO2 (post RM), ml min−1

1144

1097

790

786

1012

971

RAP (baseline), mm Hg

9

9

11

11

11

11

RAP (at max PAW), mm Hg

18

12

21

15

23

16

PF ratio (baseline), mm Hg

199

199

196

196

65

65

PF ratio (post RM), mm Hg

363

213

337

309

347

86

  1. List of Abbreviations: RM recruitment maneuver, PEEP positive end expiratory pressure, R Ratio recruitment ratio ((recruitmentM -recruitmentB)/recruitmentB × 100), ∆ CO change in cardiac output relative to baseline, ∆ RVEDV change in right ventricle end diastolic volume relative to baseline, DO 2 oxygen delivery, ∆ DO 2 change in oxygen deliver relative to baseline, PF ratio ratio of arterial partial pressure of oxygen to fraction of oxygen in inhaled air, max P AW maximum airway pressure, RAP right atrial pressures