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Table 4 Key results of Maximum Recruitment Strategy (MRS) in 20 in silico ARDS patients

From: Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome

 

All Patients

Severe ARDS

Moderate ARDS

Mild ARDS

 

mean

sd

mean

sd

mean

sd

mean

sd

PEEP (baseline), cmH2O

10.0

0

10.0

0

10.0

0

10.0

0

PEEP (post RM), cmH2O

24.5

2

25.0

0

25.0

0

21.7

6

Recruitment (baseline), %

63.3

18

49.7

11

75.7

4

88.0

11

Recruitment (at max PAW), %

93.7

3

92.4

2

94.2

3

97.7

3

CO (baseline), l min−1

11.6

0.2

11.7

0.1

11.6

0.2

11.3

0.3

CO (at max PAW), l min−1

8.3

0.3

8.4

0.2

8.2

0.2

8.1

0.3

CO (post RM), l min-1

10.3

0.2

10.3

0.1

10.2

0.1

10.4

0.1

∆ RVEDV (at max PAW), ml

−48

6.1

−49

6.2

−46

5.9

−52

4.6

∆ RVESV (at max PAW), ml

−33

21

−33

23

−43

16.2

−15

18

DO2 (baseline), ml min−1

1556

340

1316

244

1809

138

1929

194

DO2 (at max PAW), ml min−1

1398

81

1406

94

1385

74

1403

63

DO2 (post RM), ml min−1

1642

114

1595

99

1671

97

1759

124

PRA (baseline), mmHg

6.5

4

6.7

4

5.5

4

7.8

6

PRA (at max PAW), mmHg

7.8

4

8.8

4

7.3

4

4.9

0

PRA (post RM), mmHg

7.6

4

7.4

4

6.4

4

10.7

0

PF ratio (baseline), mmHg

102

85

54

10

115

50

250

125

PF ratio (at max PAW), mmHg

206

72

182

53

207

81

298

48

PF ratio (post RM), mmHg

140

78

92

23

179

82

243

78

Dynamic strain (baseline),

0.18

0.03

0.18

0.04

0.19

0.03

0.18

0.02

Dynamic strain (at max PAW)

0.10

0.02

0.12

0..02

0.10

0.02

0.09

0.01

  1. List of Abbreviations: RM recruitment maneuver, PEEP positive end expiratory pressure, CO cardiac output, ∆ RVEDV change in right ventricle end diastolic volume relative to baseline, ∆ LVEDV change in left ventricle end diastolic volume relative to baseline, ∆ RVESV change in right ventricle end systolic volume relative to baseline, ∆ LVEDV change in left ventricle end systolic volume relative to baseline, P RA right atrial pressure, DO 2 oxygen delivery, PF ratio ratio of arterial partial pressure of oxygen to fraction of oxygen in inhaled air, max P AW maximum airway pressure