Skip to main content

Table 1 Characteristics of the patients, as a whole group and divided into subgroups

From: IL-8 predicts early mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation

 

Whole group

AECOPD

AHF

AEOHS

P valueb

General characteristics

 Number of patients

46

34

8

4

 

 Age years: median (IQR)

77.1 (68.7–84.0)

76.9 (68.8–83.9)

82.3 (77.7–86.8)

65.4 (60.5–73.0)

0.035

 BMI kg/m2: median (IQR)

23.4 (20.5–36.1)

24.0 (18.8–28.2)

27.7 (21.7–39.2)

46.6 (39.3–55.2)

0.004

 Gender female %

65% (30/46)

65% (22/34)

63% (5/8)

75% (3/4)

0.054

 Active or ex-smokers %

87% (40/46)

97% (33/34)

63% (5/8)

50% (2/4)

<0.001

 FEV1%: median (IQR)

31 (24–43)

29 (22–36)

47a

43a

0.058

Variables related to AHRF

 pH: median (IQR)

7.28 (7.24–7.36)

7.31 (7.24–7.37)

7.24 (7.10–7.31)

7.30 (7.25–7.35)

0.17

 pO2 kPa: median (IQR)

7.45 (6.33–8.73)

6.85 (6.10–8.48)

7.50 (5.60–9.58)

8.40 (8.23–10.68)

0.24

 pCO2 kPa: median (IQR)

8.75 (7.78–10.5)

8.90 (7.78–10.35)

8.05 (6.38–10.73)

10.05 (8.45–11.73)

0.30

 Respiratory rate bpm: median (IQR)

26 (20–29)

26 (20–29)

24 (22–29)

25 (21–27)

0.89

 CRP mg/L: median (IQR)

15.5 (8.3–76.5)

36.5 (9.7–93.0)

8.7 (6.4–11.0)

12.5 (7.5–37.0)

0.076

 Lactate mmol/L: median (IQR)

1.40 (0.80–2.75)

1.10 (0.80–2.10)

3.80 (2.78–5.63)

1.20 (0.80–2.35)

0.09

 NPPV use first 4 h: median (IQR)

3.57 (3.50–4.00)

3.67 (3.50–4.00)

3.50 (2.50–4.00)

3.75 (3.50–4.00)

0.67

  1. IQR interquartile range, AECOPD acute exacerbation of COPD, AHF acute heart failure, AEOHS acute exacerbation of obesity hypoventilation syndrome, BMI body mass index, FEV1 forced expiratory volume in 1 s, CRP C-reactive protein, NPPV noninvasive positive pressure ventilation
  2. avariable number too small to analyse IQR
  3. bWe used Kruskal-Wallis test for all but gender and smoking status, there we used Fisher´s exact test