From: Elderly-onset hereditary pulmonary alveolar proteinosis and its cytokine profile
Present case | Tanaka et al. | Junne et al. | |
---|---|---|---|
Characteristics | Adult onset | Adult onset | Juvenile (n = 20) |
Sex | Female | Female | 85% (Female) |
Age at symptom onset (yr) | 77 | 35 | 0.2–19 |
Prognosis | Good | Poor | Good |
GM-CSF (pg/mL) | 86.61 | 124.8 | Elevated |
GM-CSF antibody (μg/mL) | ND | ND | ND |
Mutated gene | CSF2RA | CSF2RB | CSF2RA |
WLL therapy | responded | Worsened | Improved 64% |
Unchanged 14% | |||
Worsened 0% | |||
Deceased 7% |