Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

BMC Pulmonary Medicine

Table 4 Laboratory methods of studies performing Epigenome-Wide Association Studies

Study	Year	Sample analysed	Methylation Analysis Technique	Coverage Level	Blood cell-type Correction
Qiu et al. [23]	2011	Leukocytes	Bisulfite Microarrays	Infinium HumanMethylation27 BeadChip	No
Bell et al. [22]	2012	Leukocytes	Bisulfite Microarrays	Infinium HumanMethylation27 BeadChip	Yes (proportion of lymphocytes)
Marioni et al. [21]	2015	Leukocytes	Bisulfite Microarrays	Infinium HumanMethylation450 BeadChip	Yes (proportion of leukocytes^a)

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