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Table 5 Annual respiratory-related resource utilization and direct costs

From: Healthcare burden of pulmonary hypertension owing to lung disease and/or hypoxia

Type

Group 3 PH

Controls

Unadjusted DID (95% CI)

Adjusted DID (95% CI)

P value

Baseline

Follow-up

Difference

Baseline

Follow-up

Difference

Respiratory-related utilization, n

 Inpatient admissions

1.4 (4.7)

2.2 (6.0)

0.8 (5.9)

0.8 (3.0)

0.8 (3.1)

−0.1 (2.5)

0.9 (0.6-1.2)

1.1 (0.8–1.4)

<.0001

 Outpatient visits

4.0 (8.0)

5.3 (10.1)

1.3 (8.0)

1.6 (4.2)

1.6 (4.5)

−0.04 (3.9)

1.4 (1.0–1.8)

1.3 (0.9–1.7)

<.0001

 Physician office visits

2.2 (3.6)

2.6 (3.7)

0.4 (3.5)

1.5 (2.3)

1.3 (2.4)

−0.2 (2.3)

0.5 (0.4–0.7)

0.7 (0.5–0.9)

<.0001

 ED visits

0.1 (0.5)

0.2 (0.6)

0.0 (0.6)

0.1 (0.3)

0.1 (0.4)

0.0 (0.4)

0.01 (−0.02–0.04)

0.02 (−0.01–0.05)

0.28

Respiratory-related costs, US$

 Total

3405 (16,246)

5089 (36,980)

1684 (38,082)

862 (2736)

587 (2541)

−275 (3068)

1960 (376–3544)

1856 (177–3534)

0.0303

 Inpatient

2181 (15,301)

3652 (36,218)

1472 (37,958)

316 (2112)

158 (1327)

−159 (2324)

1630 (54–3207)

1511 (−160–3182)

0.0764

 Outpatient

733 (2566)

981 (2909)

248 (3138)

240 (1194)

176 (1762)

−64 (1627)

312 (165–458)

319 (164–474)

<0.0001

 Physician office

156 (454)

148 (370)

−8 (433)

67 (235)

39 (166)

−28 (246)

19 (−1–40.0)

26 (4–48)

0.0191

 ED visit

70 (796)

59 (526)

−11 (715)

12 (112)

11 (114)

−1 (139)

−11 (−41–20)

−2 (−34–30)

0.8875

  1. Values are expressed as mean (SD) unless otherwise specified. Baseline and follow-up refer to the 12-month periods pre- and post-index date, respectively
  2. “Physician office” refers to outpatient physician office visits; “outpatient” refers to all other outpatient services. ED visits that led to hospitalization were counted as both an ED visit and an inpatient visit
  3. Costs were inflated to 2013 US $ and rounded to closest dollar. Costs reflect fully paid and adjudicated medical claims paid by a third party payer. DID of healthcare costs and utilizations between the two groups from baseline to follow-up time period were analyzed by using GEE regression models adjusting for age, sex, census region, health plan type, and CCI. P < .05 was considered statistically significant
  4. CI confidence interval, DID difference-in-difference, ED emergency department, SD standard deviation