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Table 2 Comparison of lung function data between groups of patients according to the number, the size or the uni- or bilateral localization of the PAVMs

From: Effect of pulmonary arteriovenous malformations on the mechanical properties of the lungs

 

TLC (% pred.)

RV (% pred.)

VC (% pred.)

FEV1 (% pred.)

FEF25 (% pred.)

A-a O2 gradient (mmHg)

Number

 No PAVM

98.7 ± 11.7 (n = 86)

102.9 ± 26.1 (n = 86)

101.7 ± 12.4 (n = 88)

101.4 ± 12.3 (n = 88)

80.4 ± 27.8 (n = 87)

10.4 ± 8.2 (n = 84)

 1-3 PAVMs

99.4 ± 11.9 (n = 45)

99.0 ± 24.7 (n = 45)

103.8 ± 14.0 (n = 45)

102.9 ± 12.1 (n = 45)

79.1 ± 30.4 (n = 45)

13.3 ± 12.0 (n = 45)

  ≥ 4 PAVMS

101.9 ± 11.8 (n = 20)

108.7 ± 28.7 (n = 20)

100.4 ± 15.5 (n = 22)

99.7 ± 16.8 (n = 22)

78.7 ± 35.2 (n = 22)

18.2 ± 15.3 (n = 22)

 p

NS

NS

NS

NS

NS

0.009

Size

 No PAVM

98.7 ± 11.7 (n = 86)

102.9 ± 26.1 (n = 86)

101.7 ± 12.4 (n = 88)

101.4 ± 12.3 (n = 88)

80.4 ± 27.8 (n = 87)

10.4 ± 8.2 (n = 84)

 Microscopic PAVM(s)

100.7 ± 11.5 (n = 45)

97.1 ± 23.7 (n = 45)

104.5 ± 13.1 (n = 47)

103.4 ± 12.7 (n = 47)

82.2 ± 31.2 (n = 47)

10.9 ± 9.2 (n = 47)

  ≥ 1 macroscopic PAVM

99.0 ± 12.7 (n = 20)

113.0 ± 28.7 (n = 20)

98.3 ± 16.8 (n = 20)

98.0 ± 15.8 (n = 20)

71.5 ± 32.6 (n = 20)

24.5 ± 16.3 (n = 20)

 p

NS

NS

NS

NS

NS

0.0001

Uni- or bilateral

 No PAVM

98.7 ± 11.7 (n = 86)

102.9 ± 26.1 (n = 86)

101.7 ± 12.4 (n = 88)

101.4 ± 12.3 (n = 88)

80.4 ± 27.8 (n = 87)

10.4 ± 8.2 (n = 84)

 Unilateral PAVM(s)

100.1 ± 12.2 (n = 38)

101.8 ± 25.0 (n = 38)

102.7 ± 13.1 (n = 38)

102.7 ± 12.3 (n = 38)

80.4 ± 29.4 (n = 38)

11.9 ± 10.0 (n = 38)

 Bilateral PAVMs

100.2 ± 11.5 (n = 27)

102.3 ± 28.3 (n = 27)

102.6 ± 16.4 (n = 29)

100.7 ± 15.6 (n = 29)

77.2 ± 35.1 (n = 29)

18.9 ± 15.9 (n = 29)

 p

NS

NS

NS

NS

NS

0.001

  1. (PAVM = pulmonary arteriovenous malformation; TLC = total lung capacity; RV = residual volume; VC = vital capacity; FEV1 = forced expiratory volume in 1 s; FEF75 = forced expiratory flow at 75% of vital capacity; A-a O2 gradient = alveolar–arterial gradient in O2. NS = not significant)