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Table 2 Univariate Cox regression analysis of chronic hypersensitivity pneumonitis patients demonstrating mortality according to CALIPER indices (top white), visually derived CT indices (light grey), pulmonary function tests (dark grey), echocardiography, and clinical indices (lower white). ILD = Interstitial lung disease, DA = decreased attenuation, TxBx = traction bronchiectasis, PA = pulmonary artery, Ao = Aorta, PVV = pulmonary vessel volume, FEV1 = forced expiratory volume in one second, FVC = forced vital capacity, TLC = total lung capacity, DLco = diffusing capacity for carbon monoxide, Kco = Carbon monoxide transfer coefficient, CPI = composite physiologic index, RVSP = right ventricular systolic pressure, NS = not significant

From: Chronic hypersensitivity pneumonitis: identification of key prognostic determinants using automated CT analysis

 

Number of patients

Hazard ratio

P value

95.0% Confidence interval

Lower

Upper

Caliper indices

 Total ILD extent

116

1 · 02

0 · 001

1 · 01

1 · 03

 Total fibrosis extent

116

1 · 32

<0 · 0001

1 · 22

1 · 43

 Ground glass opacity

116

1 · 02

0 · 02

1 · 00

1 · 03

 Reticular pattern

116

1 · 33

<0 · 0001

1 · 22

1 · 44

 Honeycombing

116

2 · 71

0 · 001

1 · 54

4 · 76

 Emphysema

116

 

NS

  

 Normal lung

116

0 · 98

0 · 001

0 · 97

0 · 99

 PVV

116

1 · 56

<0 · 0001

1 · 31

1 · 84

Visual indices

 ILD extent

116

 

NS

  

 Fibrosis extent

116

1 · 06

<0 · 0001

1 · 04

1 · 08

 Ground glass opacity

116

0 · 98

0 · 02

0 · 97

1 · 00

 Reticular pattern

116

1 · 05

<0 · 0001

1 · 03

1 · 07

 Honeycombing

116

1 · 19

0 · 001

1 · 07

1 · 31

 Consolidation

116

 

NS

  

 Total emphysema

116

 

NS

  

 Mosaicism

116

 

NS

  

 TxBx severity

116

1 · 16

<0 · 0001

1 · 09

1 · 23

 Main PA

116

1 · 09

0 · 002

1 · 03

1 · 15

 Aorta

116

 

NS

  

 PA:Ao ratio

116

1 · 03

0 · 02

1 · 01

1 · 05

Pulmonary function indices

 FEV1

112

0 · 98

0 · 02

0 · 96

1 · 00

 FVC

112

0 · 98

0 · 006

0 · 97

0 · 99

 TLC

103

0 · 96

0 · 0001

0 · 93

0 · 98

 DLco

109

0 · 96

0 · 001

0 · 93

0 · 98

 Kco

109

 

NS

  

 CPI

108

1 · 04

0 · 001

1 · 02

1 · 07

Other indices

 ECHOCARDIOGRAPHY RVSP

58

 

NS

  

 Age

116

 

NS

  

 Gender

116

 

NS

  

 Smoking history

115

 

NS