Skip to main content

Table 2 Univariate Cox regression analysis of chronic hypersensitivity pneumonitis patients demonstrating mortality according to CALIPER indices (top white), visually derived CT indices (light grey), pulmonary function tests (dark grey), echocardiography, and clinical indices (lower white). ILD = Interstitial lung disease, DA = decreased attenuation, TxBx = traction bronchiectasis, PA = pulmonary artery, Ao = Aorta, PVV = pulmonary vessel volume, FEV1 = forced expiratory volume in one second, FVC = forced vital capacity, TLC = total lung capacity, DLco = diffusing capacity for carbon monoxide, Kco = Carbon monoxide transfer coefficient, CPI = composite physiologic index, RVSP = right ventricular systolic pressure, NS = not significant

From: Chronic hypersensitivity pneumonitis: identification of key prognostic determinants using automated CT analysis

  Number of patients Hazard ratio P value 95.0% Confidence interval
Lower Upper
Caliper indices
 Total ILD extent 116 1 · 02 0 · 001 1 · 01 1 · 03
 Total fibrosis extent 116 1 · 32 <0 · 0001 1 · 22 1 · 43
 Ground glass opacity 116 1 · 02 0 · 02 1 · 00 1 · 03
 Reticular pattern 116 1 · 33 <0 · 0001 1 · 22 1 · 44
 Honeycombing 116 2 · 71 0 · 001 1 · 54 4 · 76
 Emphysema 116   NS   
 Normal lung 116 0 · 98 0 · 001 0 · 97 0 · 99
 PVV 116 1 · 56 <0 · 0001 1 · 31 1 · 84
Visual indices
 ILD extent 116   NS   
 Fibrosis extent 116 1 · 06 <0 · 0001 1 · 04 1 · 08
 Ground glass opacity 116 0 · 98 0 · 02 0 · 97 1 · 00
 Reticular pattern 116 1 · 05 <0 · 0001 1 · 03 1 · 07
 Honeycombing 116 1 · 19 0 · 001 1 · 07 1 · 31
 Consolidation 116   NS   
 Total emphysema 116   NS   
 Mosaicism 116   NS   
 TxBx severity 116 1 · 16 <0 · 0001 1 · 09 1 · 23
 Main PA 116 1 · 09 0 · 002 1 · 03 1 · 15
 Aorta 116   NS   
 PA:Ao ratio 116 1 · 03 0 · 02 1 · 01 1 · 05
Pulmonary function indices
 FEV1 112 0 · 98 0 · 02 0 · 96 1 · 00
 FVC 112 0 · 98 0 · 006 0 · 97 0 · 99
 TLC 103 0 · 96 0 · 0001 0 · 93 0 · 98
 DLco 109 0 · 96 0 · 001 0 · 93 0 · 98
 Kco 109   NS   
 CPI 108 1 · 04 0 · 001 1 · 02 1 · 07
Other indices
 ECHOCARDIOGRAPHY RVSP 58   NS   
 Age 116   NS   
 Gender 116   NS   
 Smoking history 115   NS