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Table 1 Demographic and clinical characteristics of subjects

From: Epithelial ciliated beating cells essential for ex vivo ALI culture growth

 

Overall

N = 463

Control

N = 83

Smokers

N = 65

COPD

N = 130

Mild-Mod A

N = 61

Severe A

N = 124

Sex F (n, %)

214 (47)

49 (60)

20 (31)

22 (17)

39 (66)

84 (68)

Age (mean ± sd)

54.7 ± 14.4

50.1 ± 17.0

53.5 ± 14.2

62.4 ± 10.2

52.5 ± 14.6

51.5 ± 13.1

BMI

24.3 ± 4.7

23.5 ± 4.6

24.9 ± 4.8

23.8 ± 4.2

22.4 ± 2.8

27.9 ± 6.3

FEV1 %

78.8 ± 22.7

97.8 ± 12.9

96.4 ± 18.4

64.2 ± 20.5

89.6 ± 15.0

71.3 ± 19.1

FVC %

94.8 ± 21.7

98.2 ± 19.4

103.5 ± 21.9

88.7 ± 20.8

112.4 ± 15.4

83.5 ± 14.5

FEV1/FVC

64.8 ± 14.0

78.5 ± 9.5

75.6 ± 6.0

55.7 ± 11.1

69.8 ± 10.7

59.1 ± 13.7

ICS (n, %)

172 (37)

0 (0)

0 (0)

33 (25)

38 (62)

101 (81)

OCS (n, %)

70 (15)

6 (7)

4 (6)

4 (3)

2 (3)

54 (44)

SABA (n, %)

102 (22)

0 (0)

0 (0)

15 (12)

15 (25)

71 (57)

LABA (n, %)

165 (36)

0 (0)

0 (0)

36 (28)

28 (46)

99 (80)

LAMA (n, %)

23 (5)

0 (0)

0 (0)

18 (24)

1 (2)

3 (2)

MTP/MRS

204/259

34/49

64/1

82/48

9/52

15/109

Biopsy Number

(mean ± sd)

1.57 ± 1.09

1.58 ± 1.16

2.88 ± 0.96

1.90 ± 1.28

1.25 ± 0.85

1.07 ± 0.40

Biopsies grown by a senior operator (n, %)

259 (70)

48 (77)

32 (49)

69 (53)

37 (79)

73 (85)