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Table 1 Demographic and clinical characteristics of subjects

From: Epithelial ciliated beating cells essential for ex vivo ALI culture growth

  Overall N = 463 Control N = 83 Smokers N = 65 COPD N = 130 Mild-Mod A N = 61 Severe A N = 124
Sex F (n, %) 214 (47) 49 (60) 20 (31) 22 (17) 39 (66) 84 (68)
Age (mean ± sd) 54.7 ± 14.4 50.1 ± 17.0 53.5 ± 14.2 62.4 ± 10.2 52.5 ± 14.6 51.5 ± 13.1
BMI 24.3 ± 4.7 23.5 ± 4.6 24.9 ± 4.8 23.8 ± 4.2 22.4 ± 2.8 27.9 ± 6.3
FEV1 % 78.8 ± 22.7 97.8 ± 12.9 96.4 ± 18.4 64.2 ± 20.5 89.6 ± 15.0 71.3 ± 19.1
FVC % 94.8 ± 21.7 98.2 ± 19.4 103.5 ± 21.9 88.7 ± 20.8 112.4 ± 15.4 83.5 ± 14.5
FEV1/FVC 64.8 ± 14.0 78.5 ± 9.5 75.6 ± 6.0 55.7 ± 11.1 69.8 ± 10.7 59.1 ± 13.7
ICS (n, %) 172 (37) 0 (0) 0 (0) 33 (25) 38 (62) 101 (81)
OCS (n, %) 70 (15) 6 (7) 4 (6) 4 (3) 2 (3) 54 (44)
SABA (n, %) 102 (22) 0 (0) 0 (0) 15 (12) 15 (25) 71 (57)
LABA (n, %) 165 (36) 0 (0) 0 (0) 36 (28) 28 (46) 99 (80)
LAMA (n, %) 23 (5) 0 (0) 0 (0) 18 (24) 1 (2) 3 (2)
MTP/MRS 204/259 34/49 64/1 82/48 9/52 15/109
Biopsy Number (mean ± sd) 1.57 ± 1.09 1.58 ± 1.16 2.88 ± 0.96 1.90 ± 1.28 1.25 ± 0.85 1.07 ± 0.40
Biopsies grown by a senior operator (n, %) 259 (70) 48 (77) 32 (49) 69 (53) 37 (79) 73 (85)