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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: Regulating autonomic nervous system homeostasis improves pulmonary function in rabbits with acute lung injury

Fig. 4

Inflammatory cell infiltration and vascular permeability changes induced by HCl aspiration in groups with different treatments. a, BAL total cell count; b, BAL PMNs (%); c, BAL total protein; d, lung wet/dry ratio. For control group (n = 8), rabbits only received saline intratracheally injection (2.8 ml/kg) after surgery; for HCl groups (n = 8), ALI model was established by intratracheal injection of HCl (pH 1.5, 2.8 ml/kg); for VNS groups (n = 8), after the ALI model established by HCl, rabbits also received constant voltage stimuli (5 V, 2 ms, and 1 Hz); for THA group (n = 8), after ALI model established by HCl, rabbits also received THA (3 mg/kg) intravenous injection; and for SGB group, after ALI model established by HCl, rabbits also continuously received 0.25% bupivacaine pumping via epidural catheter (3 mg/kg). BAL, bronchoalveolar lavage; PMNs, polymorphonuclear neutrophils; VNS, vagus nerve stimulation; THA, tetrahydroaminoacridine; SGB, stellate ganglion block; * P < 0.05, compared to the control group; † P < 0.05, compared to the HCl group

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