Fig. 5

Changes of inflammatory factors in both BALF and plasma in rabbits with acute lung injury after three treatments. a, plasama IL-6 levels; b, plasama IL-10 levels; c, BAL IL-6 levels; d, BAL TNF-α levels; e, BAL IL-10 levels. For control group (n = 8), rabbits only received saline intratracheally injection (2.8 ml/kg) after surgery; for HCl groups (n = 8), ALI model was established by intratracheal injection of HCl (pH 1.5, 2.8 ml/kg); for VNS groups (n = 8), after the ALI model established by HCl, rabbits also received constant voltage stimuli (5 V, 2 ms, and 1 Hz); for THA group (n = 8), after ALI model established by HCl, rabbits also received THA (3 mg/kg) intravenous injection; and for SGB group, after ALI model established by HCl, rabbits also continuously received 0.25% bupivacaine pumping via epidural catheter (3 mg/kg). BALF, bronchoalveolar lavage fluid; VNS, vagus nerve stimulation; THA, tetrahydroaminoacridine; SGB, stellate ganglion block; * P < 0.05, compared to the control group; † P < 0.05, compared to the HCl group