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Table 2 Expiratory flows and volumes in z-scores in school children and adolescents with and without history of BPD

From: Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia

 

Mild BPD

Moderate BPD

Severe BPD

All BPD

Non-BPD

P trend

n = 13

n = 7

n = 4

n = 24

n = 20

 

Spirometry at 6–8 years

 FEV1 z-scores

−1.10** (−1.63;-0.12)

−0.63* (−1.38;-0.41)

−2.63** (−3.56;-2.33)

−1.35 *** (−2.11;-0.41)

−0.13 (−0.51;-0.58)

<0.001

 FVC z-scores

−1.09** (−1.50;-0.12)

−0.54 (−0.62;-0.02)

−2.21** (−2.92;-1.50)

−0.82*** (−1.50;0.03)

0.22 (1.18;0.70)

0.001

 FEV1/FVC z-scores

−0.05 (−1.02;0.90)

−0.26 (−2.03;0.05)

−1.90* (−2.34;-1.04)

−0.26 (−1.70;-0.16)

−0.03 (−1.23;0.59)

0.022

Spirometry at13–17 years

 FEV1 z-scores

−0.40 (−1.48;-0.10)

−0.62 (−2.03;0.38)

−2.43** (−2.95;-2.14)

−0.61* (−2.04;0.07)

−0.02 (−0.37;0.55)

0.002

 FVC z-scores

−0.31 (−0.96;0.28)

0.29 (0.00;1.63)

- 0.77* (−1.28;-0.33)

- 0.18 (−0.85;0.28)

0.35 (−0.43;0.66)

0.175

 FEV1/FVC z-scores

−0.18 (−0.94;0.12)

−1.04 (−2.80;-0.22)

−2.95** (−3.20;-2.17)

−0.82* (−2.57;-0.10)

−0.47 (−1.09;0.58)

0.001

  1. Comparing between non-BPD and BPD groups using the Wilcoxon rank-sum test. P * ≤0.05, ** ≤ 0.01, *** ≤0.001. P-values for trend using nonparametric test for trend across ordered groups. Trend test comparing Non-BPD vs mild, moderate, and severe BPD
  2. Data expressed as median (25th and 75th centiles)