From: Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia
Mild BPD | Moderate BPD | Severe BPD | All BPD | Non-BPD | P trend | |
---|---|---|---|---|---|---|
n = 13 | n = 7 | n = 4 | n = 24 | n = 20 | ||
Spirometry at 6–8 years | ||||||
FEV1 z-scores | −1.10** (−1.63;-0.12) | −0.63* (−1.38;-0.41) | −2.63** (−3.56;-2.33) | −1.35 *** (−2.11;-0.41) | −0.13 (−0.51;-0.58) | <0.001 |
FVC z-scores | −1.09** (−1.50;-0.12) | −0.54 (−0.62;-0.02) | −2.21** (−2.92;-1.50) | −0.82*** (−1.50;0.03) | 0.22 (1.18;0.70) | 0.001 |
FEV1/FVC z-scores | −0.05 (−1.02;0.90) | −0.26 (−2.03;0.05) | −1.90* (−2.34;-1.04) | −0.26 (−1.70;-0.16) | −0.03 (−1.23;0.59) | 0.022 |
Spirometry at13–17 years | ||||||
FEV1 z-scores | −0.40 (−1.48;-0.10) | −0.62 (−2.03;0.38) | −2.43** (−2.95;-2.14) | −0.61* (−2.04;0.07) | −0.02 (−0.37;0.55) | 0.002 |
FVC z-scores | −0.31 (−0.96;0.28) | 0.29 (0.00;1.63) | - 0.77* (−1.28;-0.33) | - 0.18 (−0.85;0.28) | 0.35 (−0.43;0.66) | 0.175 |
FEV1/FVC z-scores | −0.18 (−0.94;0.12) | −1.04 (−2.80;-0.22) | −2.95** (−3.20;-2.17) | −0.82* (−2.57;-0.10) | −0.47 (−1.09;0.58) | 0.001 |