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Table 3 Difference in adjusted medians of lung function when comparing BPD groups to “no BPD”

From: Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia

 

Mild BPD

Moderate BPD

Severe BPD

All BPD

Non-BPD

P trend

Static spirometrya

n = 15

n = 7

n = 4

n = 26

n = 20

 

 TLC (mL)

−464 (−1151;224)

345 (−460;1150)

18 (−938;974)

−373 (−932;186)

Ref

0.848

 RV (mL)

−148 (−536;240)

−147 (−602;307)

215 (−325;754)

−100 (−360;160)

Ref

0.773

Impulse oscillometrya

n = 16

n = 7

n = 3

n = 26

n = 22

 

 R5–20 (kPa/L/s)

0.036 (−0.019;0.090)

0.013 (−0.069;0.095)

0.340*** (0.218;0.461)

0.041 (−0.010;0.093)

Ref

0.029

 AX (kPa/L)

0.034 (−0.322;0.38)

0.134 (−0.403;0.670)

3.704*** (2.907;4.502)

0.115 (−0.187;0.418)

Ref

0.275

Ergospirometryb

n = 13

n = 7

n = 4

n = 24

n = 17

 

 VO2 (mL/kg/min)

−1.7 (−9.3;5.9)

−2.3 (−11.8;7.2)

−9.1 (−20.5;2.3)

−4.0 (−10.9;2.9)

Ref

0.069

  1. aAnalysis with linear regression on the median adjusting for age, sex and height. bAnalysis with linear regression on the median adjusting for sex. Trend test comparing Non-BPD vs mild, moderate, and severe BPD
  2. Comparing between non-BPD and BPD groups including all BPD using (a) and (b). P * ≤0.05, ** ≤ 0.01, *** ≤0.001
  3. Data presented as difference (95% CI)