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Table 1 Mean arterial pressure (Pmean), peak airway pressure (Ppaw) and blood gas measured during the course of 5h of mechanical ventilation

From: Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation

  

Pmean (mmHg)

Ppaw (mmHg)

PaO2 (mmHg)

PaCO2 (mmHg)

pH

LTV

Baseline

122.8±5.7

12.0±0.2

104.6±4.8

38.1±5.2

7.36±0.2

1 h

121.2±6.4

12.1±0.2 *

114.7±7.6

42.3±6.3

7.34±0.3

2 h

118.7±6.9

12.0±0.1 *

110.3±6.6

33.3±5.5

7.39±0.2

3 h

124.3±7.1

11.9±0.2 *

112.8±8.6

35.3±6.2

7.43±0.3

4 h

114.8±8.5

12.0±0.1 *

108.8±7.1

36.3±4.8

7.41±0.2

5 h

123.6±7.5

12.0±0.2 *

113.2±6.7

43.3±4.4

7.38±0.2

HTV

Baseline

121.3±7.7

12.2±0.2

102.2±6.1

43.1±3.5

7.32±0.4

1 h

116.6±7.8

21.9±0.2 *

118.5±7.4

48.8±4.1

7.38±0.3

2 h

114.7±5.4

22.0±0.2 *

120.8±7.7

53.1±3.7

7.41±0.4

3 h

117.3±6.8

21.9±0.2 *

114.9±10.0

47.8±4.3

7.34±0.5

4 h

112.4±6.2

22.2±0.2 *

101.1±10.1

56.8±3.6

7.36±0.4

5 h

108.4±5.7

22.0±0.2 *

84.2±10.4 *

66.1±5.0 *

7.26±0.5

HTV + SOD

Baseline

124.8±7.4

12.2±0.2

97.7±6.4

41.6±3.4

7.40±0.4

1 h

114.2±5.2

22.0±0.2 *

122.5±8.2

43.1±6.6

7.43±0.3

2 h

115.7±4.5

22.1±0.2 *

115.1±7.8

50.1±4.4

7.39±0.5

3 h

110.3±8.4

21.5±0.2 *

122.1±6.8

47.1±5.6

7.34±0.4

4 h

113.0±7.3

22.2±0.2 *

107.1±6.8

55.1±4.5

7.34±0.5

5 h

116.1±7.7

22.1±0.2 *

98.1±6.8

53.7±5.4

7.32±0.5