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Table 3 Results of multivariable Weibull regression with interval censored outcomes1 evaluating the association of PM2.5 exposure and time to methicillin susceptible Staphylococcus aureus, methicillin resistant Staphylococcus aureus, Stenotrophomonas maltophilia, and Achromobacter xylosoxidans acquisition for young children with cystic fibrosis, 2003–2009

From: Air pollution exposure is associated with MRSA acquisition in young U.S. children with cystic fibrosis

PM2.5 metric

 

Nearest monitor

IDW: 50 miles

IDW: 30 miles

IDW: 10 miles

HR (95% CI)

HR (95% CI)

HR (95% CI)

HR (95% CI)

MSSA

0.91 (0.77, 1.08)

0.93 (0.77, 1.13)

0.97 (0.80, 1.17)

0.90 (0.71, 1.15)

MRSA

1.48 (1.14, 1.93)

1.68 (1.24, 2.27)

1.56 (1.13, 2.14)

1.78 (1.17, 2.69)

S. maltophilia

1.34 (1.07, 1.68)

1.30 (1.00, 1.65)

1.28 (0.99, 1.66)

1.10 (0.79, 1.53)

A. xylosoxidans

1.48 (0.91, 2.41)

1.44 (0.83, 2.53)

1.42 (0.78, 2.58)

1.51 (0.68, 3.34)

  1. PM 2.5 particulate matter ≤2.5 μm in aerodynamic diameter, IDW inverse distance weighted, HR hazard ratio, CI confidence interval, MSSA methicillin susceptible Staphylococcus aureus, MRSA methicillin resistant Staphylococcus aureus, S maltophilia Stenotrophomonas maltophilia, A xylosoxidans, Achromobacter xylosoxidans
  2. 1All regression models were adjusted for: sex, race, ethnicity, insurance status, rural urban commuting area, diagnosis by newborn screening, age at diagnosis of CF, and CFTR mutation class. Results of regression models reflect the hazard ratio associated with a 10 μg/m3 increase in PM2.5 exposure. Hazard ratios that are significantly different from 1.00 (P < 0.05) are in italics
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BMC Pulmonary Medicine

ISSN: 1471-2466

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