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Table 2 Therapy and prognosis of study participants stratified by HRCT pattern

From: Serological and morphological prognostic factors in patients with interstitial pneumonia with autoimmune features

  

HRCT pattern

Total

OP

NSIP + OP

NSIP

Number of patients, n

98

20

15

63

5-year survival, %

71.1%

100.0%

86.7%

58.6%

Treatment,n (%)

78

(79.6%)

19

(95%)

15

(100%)

44

(69.8%)

 corticosteroid, n(%)

17

(17.3%)

15

(75%)

6

(40%)

6

(9.5%)

 corticosteroid + ISa, n (%)

48

(49.0%)

4

(20%)

9

(60%)

35

(55.6%)

 corticosteroid + IS + pirfenidone, n (%)

1

(1.0%)

0

(0%)

0

(0%)

1

(1.6%)

 pirfenidone, n (%)

2

(2.0%)

0

(0%)

0

(0%)

2

(3.2%)

Response to Treatment, n (%)

70

(71.4%)

19

(95%)

15

(100%)

36

(57.1%)

 Improve/stable/deteriorate, n

45/20/5

18/1/0

14/1/0

13/18/5

Overall death, n (%)

27

(27.6%)

1

(5%)

3

(20%)

23

(36.5%)

Death due to respiratory failure, n (%)

15

(15.3%)

0

(0%)

1

(6.7%)

14

(22.2%)

 Acute exacerbation, n (%)

5

(5.1%)

0

(0%)

0

(0%)

5

(7.9%)

  1. Data are presented as No. (%). NSIP non-specific interstitial pneumonia, NSIP + OP NSIP with OP overlap, OP organizing penumonia. aIS = immnuno suppressants other than corticosteroid which included azathioprine, cyclsporin, cyclophosphamide and tacrolimus