Skip to main content

Table 4 Prognostic survival factors in patients with IPAF using univariate cox model

From: Serological and morphological prognostic factors in patients with interstitial pneumonia with autoimmune features

 

Number

HR

[95% CI]

p value

Age

98

1.07

[1.03–1.11]

<0.01

Male sex

98

1.98

[0.92–4.25]

0.08

Smoker

98

1.27

[0.59–2.73]

0.54

Radiologic NSIP pattern vs. NSIP + OP or OP pattern

98

4.00

[1.38–11.6]

0.01

SScAb positive IPAF

98

2.88

[1.36–6.11]

0.01

Anti-CCP positive IPAF

98

0.87

[0.26–2.91]

0.82

Anti-SSB positive IPAF

98

NE

 

1.00

ARS Ab positive IPAF

98

0.25

[0.03–1.89]

0.18

BAL fluid Lymphocytes > 15%

75

0.29

[0.10–0.82]

0.02

BAL fluid neutrophil > 3%

75

1.99

[0.65–6.06]

0.23

BAL fluid eosinophil > 1%

75

0.63

[0.25–1.59]

0.33

FVC%predicted

85

0.98

[0.96–1.00]

0.08

DLCO%predicted

85

0.99

[0.97–1.02]

0.55

  1. Anti-CCP uclic anti-citrullinated peptide, ARS Ab anti-tRS antibody, BAL bronchoalveolar lavage, CI confidence interval, DLCO diffusing capacity of the lung for carbon monoxide, FVC forced vital capacity, IPAF Interstitial pneumonia with autoimmune features, NE not evaluable, NSIP non-specific interstitial pneumonia, NSIP + OP NSIP with OP overlap, OP organizing penumonia, SScAb SSc-specific and SSc-related antibodies