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Exploring efficacy and safety of oral Pirfenidone for progressive, non-IPF lung fibrosis (RELIEF) - a randomized, double-blind, placebo-controlled, parallel group, multi-center, phase II trial

  • Jürgen Behr1Email author,
  • Petra Neuser2,
  • Antje Prasse3,
  • Michael Kreuter4,
  • Klaus Rabe5,
  • Carmen Schade-Brittinger2,
  • Jasmin Wagner6 and
  • Andreas Günther6, 7
BMC Pulmonary MedicineBMC series – open, inclusive and trusted201717:122

Received: 30 December 2016

Accepted: 23 August 2017

Published: 6 September 2017

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
30 Dec 2016 Submitted Original manuscript
5 Feb 2017 Author responded Author comments - Juergen Behr
Resubmission - Version 2
5 Feb 2017 Submitted Manuscript version 2
21 Mar 2017 Reviewed Reviewer Report - Rade Tomic
1 Apr 2017 Reviewed Reviewer Report - Giovanni Ferrara
4 May 2017 Author responded Author comments - Juergen Behr
Resubmission - Version 3
4 May 2017 Submitted Manuscript version 3
11 Aug 2017 Reviewed Reviewer Report - Rade Tomic
Resubmission - Version 4
Submitted Manuscript version 4
23 Aug 2017 Editorially accepted
6 Sep 2017 Article published 10.1186/s12890-017-0462-y

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

Department of Internal Medicine V, Comprehensive Pneumology Center, University of Munich (LMU) and Asklepios Fachkliniken München-Gauting, Munich, Germany
Coordinating Center for Clinical Trials, Philipps University of Marburg, Marburg, Germany
Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
Department of Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany
Lungenclinic Grosshansdorf and University of Kiel, Kiel, Germany
Department of Internal Medicine II, University of Giessen-Marburg Lung Center, Justus-Liebig University Giessen, Giessen, Germany
AGAPLESION Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany