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Table 3 Most important treatment goals with current treatment

From: Unmet needs in the treatment of idiopathic pulmonary fibrosis―insights from patient chart review in five European countries

Goal, n (%)

Pooled population

Treated

Untreated

Treated N = 828

Untreated N = 405

Expert N = 551

Non-expert N = 277

Expert N = 176

Non-expert N = 229

Prolong survival/reduce risk of mortality

402 (48.6)

174 (43.0)

273 (49.5)

129 (46.6)

80 (45.5)

94 (41.0)

Improvement of quality of life

314 (37.9)

179 (44.2)*

194 (35.2)

120 (43.3)

75 (42.6)

104 (45.4)

Overall disease stabilization

334 (40.3)

152 (37.5)

234 (42.5)

100 (36.1)

64 (36.4)

88 (38.4)

Stabilization of predicted% FVC

279 (33.7)

56 (13.8)**

176 (32.0)

102 (36.8)

23 (13.1)

33 (14.4)

Stabilization of quality of life

248 (30.0)

135 (33.3)

164 (29.8)

83 (30.0)

70 (39.8)

65 (28.4)

Improvement of symptoms

236 (28.5)

142 (35.1)*

161 (29.2)

76 (27.4)

57 (32.4)

85 (37.1)

Stabilization of symptoms

215 (26.0)

143 (35.3)**

135 (24.5)

81 (29.2)

68 (38.6)

75 (32.8)

Decrease in number of exacerbations

208 (25.1)

94 (23.2)

153 (27.8)

55 (19.9)

40 (22.7)

53 (23.1)

Avoid pulmonary hospitalizations

156 (18.8)

122 (30.1)**

101 (18.3)

55 (19.9)

46 (26.1)

76 (33.2)

Stabilization of predicted% DLco

92 (11.1)

19 (4.7)**

61 (11.1)

31 (11.2)

3 (1.7)

15 (6.6)

  1. DLco carbon monoxide diffusing capacity; FVC forced vital capacity
  2. Respondents were asked to pick the three most important goals; for individual questions asked, please refer to Additional file 2
  3. p values represent treated population versus untreated population. * p ≤ 0.05; ** p ≤ 0.01