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Table 1 Patient demographics and clinical characteristics of the LGRC IPF cohort

From: Unsupervised gene expression analyses identify IPF-severity correlated signatures, associated genes and biomarkers

Disease Group UIP/IPF Control p Value
Number 131 12  
Age—mean (SD) 62.6 (12.2) 64.1 (8.2) 0.5631 a
%predicted FEV1 (SD) 71.37 (19.00) 94.33 (9.86) 6.3E-5 a
%predicted FVC (SD) 64.78 (17.41) 91.75 (7.44) 4.3E-7 a
%predicted DLCO (SD) 49.33 (18.14) 97.00 (21.30) 1.1E-11 a
Gender—% male 67.2 25 0.0375 b
  1. IPF idiopathic pulmonary fibrosis; LGRC Lung Genome Research Consortium; UIP usual interstitial pneumonia; FVC forced vital capacity; FEV1 forced expiratory volume in 1 s; DCLO diffusing capacity of the lung for carbon monoxide; SD standard deviation
  2. aBy two-tailed Student’s t-Test
  3. bBy χ2 test