Fig. 2

Geometric means (with 95% confidence intervals) of total viable counts expressed as colony-forming units (CFU)/mL of Pseudomonas aeruginosa in sputum samples collected from adult patients with cystic fibrosis at start-of-treatment, during treatment and end-of-treatment time-points for intravenous antibiotic therapy of a pulmonary exacerbation, and at follow-up. Single-strain infection, black circle; mixed-strain infection, grey circle. There was no statistically significant difference between time-points of sputum collection and total viable counts (P = 0.1, repeated measures ANOVA; based on log-transformed CFU/mL from 10 patients, who each provided four sputum samples). There was also no statistically significant difference between time-points of sputum collection and total viable counts of those with single-strain infections (P = 0.5, repeated measures ANOVA; based on log-transformed CFU/mL from 5 patients, who each provided four sputum samples) or mixed-strain infections (P = 0.2, repeated measures ANOVA; based on log-transformed CFU/mL from 5 patients)