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Table 3 Variables that were most significantly associated with low survival in the entire cohort (Cox proportional-hazards model)

From: A rise in mean platelet volume during hospitalization for community-acquired pneumonia predicts poor prognosis: a retrospective observational cohort study

Variable

p-value

Relative risk

95% confidence interval

Model with Pneumonia Severity Index score

 Agea

< 0.001

1.60

1.44–1.79

 Pneumonia Severity Index scoreb

< 0.001

1.85

1.53–2.22

 Cerebrovascular disease

< 0.001

2.15

1.68–2.74

 ΔMPV ≥ 0.6 fL

0.001

1.26

1.11–1.43

 History of malignancy

0.001

1.78

1.31–2.44

 Heart failure

0.003

1.46

1.13–1.88

 Hypoalbuminemia on admission

0.009

1.43

1.14–1.78

 Chronic lung disease

0.015

1.32

1.06–1.64

Model with CURB-65 class

 Agea

< 0.001

1.75

1.58–1.95

 Cerebrovascular disease

< 0.001

2.37

1.86–3.02

 Heart failure

< 0.001

1.77

1.39–2.25

 CURB-65c

< 0.001

1.30

1.14–1.49

 History of malignancy

< 0.001

1.86

1.36–2.55

 ΔMPV ≥ 0.6 fL

0.001

1.23

1.08–1.41

 Hypoalbuminemia on admission

0.003

1.44

1.16–1.80

 Chronic lung disease

0.006

1.36

1.09–1.69

 Female sex

0.019

0.77

0.62–0.96

  1. ΔMPV: MPV (mean platelet volume) on discharge minus MPV on admission; CURB-65: assigning 1 point each for confusion, blood urea nitrogen > 19 g/dl, respiratory rate ≥ 30 breaths/min, low blood pressure and age ≥ 65 years. aFor each 10 year increment. bFor each 50 points increment. cFor each 1 point increment