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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

Fig. 5

Effect of Arg1 ablation in the lung on the pulmonary concentration of inflammatory cytokines, chemokines, and OVA-specific IgE. Black bars represent Arg1-Con mice and white bars Arg1-KOTie2 mice. Treatment of the mice (PBS/OVA or OVA/OVA) is indicated. The pulmonary concentrations of IL-4, IL-13, IL-5, CCL11, IL-10, TNFα and IFNγ (pg/mg total protein), and OVA-specific IgE (ng/mL) in plasma are shown as means ± SEM (n = 7-8 mice per group). Significance symbols: *: P < 0.05 (OVA/OVA vs. PBS/OVA Arg1-Con); #: P < 0.05 (OVA/OVA vs. PBS/OVA Arg1-KOTie2); ‡: P < 0.05 (OVA/OVA Arg1-KOTie2 vs OVA/OVA Arg1-Con)

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