Fig. 5From: Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female miceEffect of Arg1 ablation in the lung on the pulmonary concentration of inflammatory cytokines, chemokines, and OVA-specific IgE. Black bars represent Arg1-Con mice and white bars Arg1-KOTie2 mice. Treatment of the mice (PBS/OVA or OVA/OVA) is indicated. The pulmonary concentrations of IL-4, IL-13, IL-5, CCL11, IL-10, TNFα and IFNγ (pg/mg total protein), and OVA-specific IgE (ng/mL) in plasma are shown as means ± SEM (n = 7-8 mice per group). Significance symbols: *: P < 0.05 (OVA/OVA vs. PBS/OVA Arg1-Con); #: P < 0.05 (OVA/OVA vs. PBS/OVA Arg1-KOTie2); ‡: P < 0.05 (OVA/OVA Arg1-KOTie2 vs OVA/OVA Arg1-Con)Back to article page